@prefix dc: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAhQuOdqh0N9M1ehRgmemMQ7s_-0SP0afrSPvmm3sUMVw> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAhQuOdqh0N9M1ehRgmemMQ7s_-0SP0afrSPvmm3sUMVw#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix sfam: <http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix hasAnnotation: <http://semanticscience.org/resource/SIO_000255> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 hasAgent: sub:_2 ;
    a go:0005525 .
  sub:_2 geneProductOf: sfam:RHO%20Family ;
    a Protein: .
  sub:_3 hasAgent: sub:_4 ;
    a go:0005525 .
  sub:_4 geneProductOf: sfam:RAS%20Family ;
    a Protein: .
  sub:_5 hasAgent: sub:_6 ;
    a go:0016301 .
  sub:_6 geneProductOf: hgnc:9829 ;
    a Protein: .
  sub:_7 rdf:object sub:_5 ;
    rdf:predicate belv:directlyIncreases ;
    rdf:subject sub:_3 ;
    a rdf:Statement .
  sub:_8 occursIn: mesh:D003593 , species:9606 ;
    hasAnnotation: sub:_9 ;
    rdf:object sub:_7 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:_9 dc:subject "TextLocation" ;
    rdf:value "Review" .
  sub:assertion rdfs:label "gtp(p(SFAM:\"RAS Family\")) => kin(p(HGNC:RAF1))" , "gtp(p(SFAM:\"RHO Family\")) -> (gtp(p(SFAM:\"RAS Family\")) => kin(p(HGNC:RAF1)))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ;
    dce:title "BEL Framework Small Corpus Document" ;
    dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ;
    pav:authoredBy sub:_11 ;
    pav:version "20131211" .
  sub:_10 prov:value """The Rho family of small GTPases, consisting of Rho, Rac, and cyclin-dependent kinase
(Cdc) 42, regulate cytoskeletal organization during the cell cycle and also
mediate Ras-induced activation of Raf, especially C-Raf.134-136  These GTPases do
not directly bind to Raf but, instead, signal by activating downstream kinases.
Rho signals by activating the serine/threonine protein kinases N1 and N2 and Rho-associated
kinase 1, whereas Rac and Cdc42 signal through p21-activated kinase
(PAK).134-136""" ;
    prov:wasQuotedFrom pubmed:16170185 .
  sub:_11 rdfs:comment "support@belframework.org" ;
    rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:16170185 ;
    prov:wasDerivedFrom beldoc: , sub:_10 .
}
sub:pubinfo {
   this: dc:created "2014-07-03T14:31:15.645+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}