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http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_4 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_3 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_6 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_5 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_1 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#assertion http://www.w3.org/2000/01/rdf-schema#label complex(a(CHEBI:genistein),p(MGI:Cftr)) -| (p(MGI:Cftr) -> sec(a(SCHEM:"Chloride(1-)"))) http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#assertion http://www.w3.org/2000/01/rdf-schema#label p(MGI:Cftr) -> sec(a(SCHEM:"Chloride(1-)")) http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_8 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_7 http://www.w3.org/ns/prov#value The data suggest that genistein may inhibit CFTR by two mechanisms. First, it may interact with NBD1 to potently inhibit channel opening. Second, it may bind within the CFTR pore to weakly block Cl- permeation. http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_7 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10766914 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_8 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10766914 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#_7 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo#pubinfo http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo http://purl.org/dc/terms/created 2014-07-03T14:29:50.739+02:00 http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAhnzgH8vrb4AbPg1JI98AGr6gdZWt4McqDZgkExWliZo http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234