@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAhyezv4brRBY03FsXHlXAdSiM6UjK8iaiyC-j13C_T5I
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAhyezv4brRBY03FsXHlXAdSiM6UjK8iaiyC-j13C_T5I#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix proteinModification: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
> .
@prefix psimod: <
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix atcc: <
http://www.lgcstandards-atcc.org/Products/All/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
belv:variantOf
hgnc:391
;
a
proteinModification:
,
psimod:00696
.
sub:_2
hasAgent:
sub:_3
;
a
go:0016301
.
sub:_3
geneProductOf:
hgnc:391
;
a
Protein:
.
sub:_4
occursIn:
atcc:CCL-2.aspx
,
species:9606
;
rdf:object
sub:_2
;
rdf:predicate
belv:directlyIncreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"p(HGNC:AKT1,pmod(P,S,473)) => kin(p(HGNC:AKT1))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_6
;
pav:version
"1.4" .
sub:_5
prov:value
"As shown in Fig. 2 B, subconfluent HeLa cultures have relatively low levels of active PKB, as detected by antibodies specifically recognizing PKB phosphorylated on serine 473. Phosphorylation of PKB is fully inhibitable by treatment with the specific PI 3-kinase inhibitor LY294002. Sparse cultures have barely detectable levels of phosphorylated PKB; however, dense cultures have much more activated PKB, whereas the total levels of PKB protein remain constant under all conditions examined." ;
prov:wasQuotedFrom
pubmed:11535620
.
sub:_6
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:11535620
;
prov:wasDerivedFrom
beldoc:
,
sub:_5
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:29:58.073+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}