sub:provenance { beldoc:dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ; dce:title "BEL Framework Small Corpus Document" ; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ; pav:authoredBysub:_7 ; pav:version "1.6" . sub:_6prov:value """Recently, it has been shown that ΔNp63a is also overexpressed in HNSCC cell lines (including JHU-012) and in these cells, it acts as a crucial survival factor by suppressing p73-dependent apoptosis.29,32–34 Knockdown of ΔNp63 induces the proapoptotic bcl-2-family members Puma and Noxa, and both their induction and cell death are p53-independent, but require transactivating isoforms of p73. The inhibition of p73-dependent transcription by DNp63a involves both direct promoter binding and physical sequestration of p73 by protein–protein interaction.29,34–35""" ; prov:wasQuotedFrompubmed:18483491 . sub:_7rdfs:comment "support@belframework.org" ; rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:18483491 ; prov:wasDerivedFrombeldoc: , sub:_6 . }