@prefix dc: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix go: .
@prefix hasAgent: .
@prefix mesh: .
@prefix occursIn: .
@prefix hasAnnotation: .
@prefix species: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 geneProductOf: hgnc:15979;
a Protein: .
sub:_2 hasAgent: sub:_3;
a go:0042789 .
sub:_3 geneProductOf: hgnc:12003;
a Protein: .
sub:_4 occursIn: mesh:D002294, mesh:D006258, mesh:D053595, species:9606;
hasAnnotation: sub:_5;
rdf:object sub:_2;
rdf:predicate belv:directlyDecreases;
rdf:subject sub:_1;
a rdf:Statement .
sub:_5 dc:subject "TextLocation";
rdf:value "Abstract" .
sub:assertion rdfs:label "p(HGNC:TP63) =| tscript(p(HGNC:TP73))" .
}
sub:provenance {
beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
dce:title "BEL Framework Small Corpus Document";
dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
pav:authoredBy sub:_7;
pav:version "1.6" .
sub:_6 prov:value """Recently, it has been shown that ΔNp63a is also overexpressed in HNSCC cell lines
(including JHU-012) and in these cells, it acts as a crucial survival factor by
suppressing p73-dependent apoptosis.29,32–34 Knockdown of ΔNp63 induces the proapoptotic
bcl-2-family members Puma and Noxa, and both their induction and cell
death are p53-independent, but require transactivating isoforms of p73. The inhibition
of p73-dependent transcription by DNp63a involves both direct promoter binding
and physical sequestration of p73 by protein–protein interaction.29,34–35""";
prov:wasQuotedFrom pubmed:18483491 .
sub:_7 rdfs:comment "support@belframework.org";
rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:18483491;
prov:wasDerivedFrom beldoc:, sub:_6 .
}
sub:pubinfo {
this: dc:created "2014-07-03T14:29:32.689+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}