sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_4 ; pav:version "1.4" . sub:_3prov:value "prohibitin regulates E2F function Rb repressed E2F-mediated transcriptional activation through recruitment of complexes such as HDAC and Brg-1/Brm Co-repressors such as NcoR mediate the above process Rb and Prohibitin respond to different signalling pathways - Adenovirus E1A and cyclin-dependent kinases effect Rb and not Probitin - Stimulation of B cells through IgM releases prohibitin-mediated repression of E2F Viral oncoprotien SV40T inactivates Rb SV40T blocks interaction of Prohibitn with co-repressors, Brg-1 and Brm in vivo." ; prov:wasQuotedFrompubmed:12065415 . sub:_4rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:12065415 ; prov:wasDerivedFrombeldoc: , sub:_3 . }