@prefix dct: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 hasPart: sub:_2, sub:_3;
    a ProteinComplex: .
  
  sub:_10 occursIn: species:9606;
    rdf:object sub:_9;
    rdf:predicate belv:decreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:_2 geneProductOf: hgnc:1984;
    a Protein: .
  
  sub:_3 geneProductOf: hgnc:9446;
    a Protein: .
  
  sub:_4 hasPart: sub:_5, sub:_6;
    a ProteinComplex: .
  
  sub:_5 geneProductOf: hgnc:9445;
    a Protein: .
  
  sub:_6 geneProductOf: hgnc:9446;
    a Protein: .
  
  sub:_7 hasAgent: sub:_8;
    a go:0042789 .
  
  sub:_8 geneProductOf: hgnc:11366;
    a Protein: .
  
  sub:_9 rdf:object sub:_7;
    rdf:predicate belv:increases;
    rdf:subject sub:_4;
    a rdf:Statement .
  
  sub:assertion rdfs:label "complex(p(HGNC:CISH),p(HGNC:PRLR)) -| (complex(p(HGNC:PRL),p(HGNC:PRLR)) -> tscript(p(HGNC:STAT5A)))",
      "complex(p(HGNC:PRL),p(HGNC:PRLR)) -> tscript(p(HGNC:STAT5A))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_12;
    pav:version "1.4" .
  
  sub:_11 prov:value "We demonstrate that CIS produces a 70% inhibition of PRL signaling by a mechanism distinct from, and downstream of, the effect of SOCS-1 on JAK2. This inhibition involves association with the PRL receptor (PRLR), resulting in the inhibition of signal transducer and activator of transcription 5 (STAT5) activation. CIS binds the PRLR but inhibits signal transducer and activator of transcription 5 rather than JAK2.";
    prov:wasQuotedFrom pubmed:11713228 .
  
  sub:_12 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:11713228;
    prov:wasDerivedFrom beldoc:, sub:_11 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:29:59.175+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}