http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#Head http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#provenance http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#pubinfo http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_2 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_1 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_3 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_10 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_10 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_9 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_10 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_10 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_1 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_10 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1984 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9446 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_4 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_5 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_4 http://purl.obolibrary.org/obo/BFO_0000051 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_6 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0043234 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_5 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9445 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_6 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9446 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_6 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_7 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_8 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_7 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0042789 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_8 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=11366 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_8 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_9 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_7 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_9 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_9 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_4 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_9 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.w3.org/2000/01/rdf-schema#label complex(p(HGNC:CISH),p(HGNC:PRLR)) -| (complex(p(HGNC:PRL),p(HGNC:PRLR)) -> tscript(p(HGNC:STAT5A))) http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.w3.org/2000/01/rdf-schema#label complex(p(HGNC:PRL),p(HGNC:PRLR)) -> tscript(p(HGNC:STAT5A)) http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_12 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_11 http://www.w3.org/ns/prov#value We demonstrate that CIS produces a 70% inhibition of PRL signaling by a mechanism distinct from, and downstream of, the effect of SOCS-1 on JAK2. This inhibition involves association with the PRL receptor (PRLR), resulting in the inhibition of signal transducer and activator of transcription 5 (STAT5) activation. CIS binds the PRLR but inhibits signal transducer and activator of transcription 5 rather than JAK2. http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_11 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11713228 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_12 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11713228 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#_11 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4#pubinfo http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://purl.org/dc/terms/created 2014-07-03T14:29:59.175+02:00 http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAib5U4PzfgRxUPdm0M43CHp61E3qddZ3mUEUivFwCyj4 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234