sub:provenance { beldoc:dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ; dce:title "BEL Framework Small Corpus Document" ; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ; pav:authoredBysub:_7 ; pav:version "20131211" . sub:_6prov:value """HCPTPA overexpression inhibits VEGFinduced VEGFR2 autophosphorylation, EC migration, and proliferation (46). High cell density-enhanced PTP1 (DEP- 1)/CD148 attenuates phosphorylation of VEGFR2 in contact-inhibited confluent ECs (40). A small molecule inhibitor of PTP1B enhances VEGF-induced VEGFR2 autophosphoryla- tion, migration, and proliferation of EC, as well as neovascularization in a mouse matrigel model (92). Angiopoietin-1 stimulates association of SHP-2 to the phosphorylated Tie-2 receptor (47), which in turn inhibits PI3 kinase-dependent signaling pathways leading to EC migration.""" ; prov:wasQuotedFrompubmed:17511588 . sub:_7rdfs:comment "support@belframework.org" ; rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:17511588 ; prov:wasDerivedFrombeldoc: , sub:_6 . }