sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_10 ;
    pav:version "1.4" .
  sub:_10 rdfs:label "Selventa" .
  sub:_9 prov:value "The proteins Clock and Bmal1 form a heterodimer which activates the transcription of the Per gene from the E-box elements in its promoter region. Protein products of Per act together with Cry proteins to inhibit Per transcription, thus closing the autoregulatory feedback loop. We found that Dec1 and Dec2, basic helix-loop-helix transcription factors, repressed Clock/Bmal1-induced transactivation of the mouse Per1 promoter through direct protein-protein interactions with Bmal1 and/or competition for E-box elements." ;
    prov:wasQuotedFrom pubmed:12397359 .
  sub:assertion prov:hadPrimarySource pubmed:12397359 ;
    prov:wasDerivedFrom beldoc: , sub:_9 .
}