@prefix dc: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAkYneEOocU2QnYBHiCFItH4qoJd6LaqMb1M8CHRVWgms
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAkYneEOocU2QnYBHiCFItH4qoJd6LaqMb1M8CHRVWgms#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix hasAnnotation: <
http://semanticscience.org/resource/SIO_000255
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
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sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0003674
.
sub:_2
geneProductOf:
hgnc:11916
;
a
Protein:
.
sub:_3
occursIn:
mesh:D015603
,
species:9606
;
hasAnnotation:
sub:_4
;
rdf:object
mesh:D002294
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:_4
dc:subject
"TextLocation" ;
rdf:value
"Results" .
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sub:provenance
{
beldoc:
dce:description
"Approximately 2000 hand curated statements drawn from 57 PubMeds." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All Rights Reserved." ;
dce:title
"BEL Framework Small Corpus Document" ;
dc:license
"Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ;
pav:authoredBy
sub:_6
;
pav:version
"1.6" .
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prov:value
"""In agreement with this, antibody-mediated TNFR1 blockade significantly inhibited s.c.
tumor growth of three independent SCC tumor lines, A431, SCC25, and CAL27 (Supplementary
Fig. S8A). To determine if TNFR1 action in this context is tumor cell
intrinsic, we used retroviral-mediated RNA interference to decrease TNFR1 expression.
Reduced levels of TNFR1, as confirmed by immunoblotting, significantly
inhibited s.c. growth of Ras-driven tumors and SCC lines (Supplementary Fig. S8B).""" ;
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pubmed:17440097
.
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beldoc:
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sub:_5
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sub:pubinfo
{
this:
dc:created
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xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}