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[CRBN depletion is initially cytotoxic to human myeloma cells, but surviving cells with stable CRBN depletion become highly resistant to both lenalidomide and pomalidomide, but not to the unrelated drugs bortezomib, dexamethasone, and melphalan.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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