. . . . . . . . . . . . . . "p(HGNC:RCAN1) -| phos(complex(NCH:\"Calcineurin Complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Interestingly, co-expression of DSCR1 strongly inhibited the induction of the IL-2 reporter by co-stimulation with PMA and ionophore. Similarly, DSCR1115-197, the truncated version of DSCR1 that retained CaNA binding activity, was able to act as a dose-dependent inhibitor, though not as efficiently as DSCR1 full-length. In contrast, co-expression of DSCR11-156, the mutant incapable of CaNA binding, had no effect on the activation assay, strongly suggesting that the inhibition caused by DSCR1 is mediated through calcineurin binding. ZAKI-4 was also able to inhibit calcineurin function, as measured by its ability to suppress IL-2 reporter activation (Fig. 5A)." . . "Selventa" . . . . "2014-07-03T14:29:51.347+02:00"^^ . . .