. . . . . . . . . . . . . . . "p(HGNC:CTNNB1) => tscript(p(HGNC:AR))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Moreover, we show that the repression of AR activity by LY294002 is mediated through phosphorylation and inactivation of GSK3beta, a downstream substrate of PI3K/Akt, which results in the nuclear accumulation of beta-catenin The activation of Akt results in the phosphorylation of a number of downstream substrates such as glycogen synthase kinase (GSK3) It has been shown that GSK3 plays an important role in the Wnt pathway by regulating the degradation of -catenin Recently, a specific protein-protein interaction between -catenin and AR was identified by us and others (22, 23). Through this interaction, -catenin augments the ligand-dependent activity of AR in prostate cancer cells." . . "Selventa" . . . . "2014-07-03T14:30:03.713+02:00"^^ . . .