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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAlK8VvslBuabhBaUrpz0QuYsiooktumy8p4HXYE8THo4#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAlK8VvslBuabhBaUrpz0QuYsiooktumy8p4HXYE8THo4#_6 http://www.w3.org/ns/prov#value # Ariadne: Results (Fig. 9 A) show that the presence of etaPKC triggers the activation of ERK5 to phosphorylate MEF2C in a manner that is dependent on MEK5. [Regulation] Consistent with the role of the aPKCs in the MEK5-ERK5 pathway, we show that zetaPKC and lambda/iotaPKC activate the Jun promoter through the MEF2C element, a well-established target of ERK5. 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