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a(SCHEM:"serum insulin") -> r(HGNC:PIK3R1)
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a(SCHEM:Sirolimus) -| (a(SCHEM:"serum insulin") -> r(HGNC:PIK3R1))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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In cultured human myotubes, up-regulation of p85alpha, p55alpha and p50alpha mRNAs by insulin was abolished by LY294002 (10 microM) and by rapamycin (50 nM), suggesting that the PI 3-kinase/protein kinase B/p70 S6 kinase pathway could be involved in the stimulation of grb-1 gene expression by insulin in human muscle cells.
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Selventa
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2014-07-03T14:29:58.954+02:00
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