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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAlXGIc99ZFmfloYcccyHM_WNvXK45eZEWnxxuic-X1ZM#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAlXGIc99ZFmfloYcccyHM_WNvXK45eZEWnxxuic-X1ZM#_4 http://www.w3.org/ns/prov#value 3.3. The p38 MAPK in senescence and tumor suppression The description of a possible p38 MAPK/p21/HBP1 pathway coincides with several reports for possible roles of p38 MAPK in senescence and tumor suppression. Senescence is characterized as an irreversible cell cycle arrest that occurs upon extended passage of cells in culture. 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