@prefix dcterms: <
http://purl.org/dc/terms/
> .
@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAlxItDZ9SpfN2qnLVLStEZhSKn4pO-PtBelVXQnp2clQ
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAlxItDZ9SpfN2qnLVLStEZhSKn4pO-PtBelVXQnp2clQ#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0016301
.
sub:_2
geneProductOf:
hgnc:6871
;
a
Protein:
.
sub:_3
belv:translocationFrom
go:0005737
;
belv:translocationOf
sub:_4
;
belv:translocationTo
go:0005634
.
sub:_4
geneProductOf:
hgnc:6767
;
a
Protein:
.
sub:_5
occursIn:
species:9606
;
rdf:object
sub:_3
;
rdf:predicate
belv:decreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"kin(p(HGNC:MAPK1)) -| tloc(p(HGNC:SMAD1),GOCCACC:\"GO:0005737\",GOCCACC:\"GO:0005634\")" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_7
;
pav:version
"1.4" .
sub:_6
prov:value
"Erk phosphorylates serine residues in the linker regions of Smad1 (Kretzschmar et al., 1997), Smad2 and Smad3 (Kretzschmar et al., 1999), and substitution of these serines by negatively charged residues inhibits nuclear translocation of Smads and thus signalling." ;
prov:wasQuotedFrom
pubmed:11792802
.
sub:_7
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:11792802
;
prov:wasDerivedFrom
beldoc:
,
sub:_6
.
}
sub:pubinfo
{
this:
dcterms:created
"2014-07-03T14:30:00.301+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}