@prefix dc: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAmAAnlXJleYiY43IUyOrGgdAaVhachb4I9ODpMQIJeJc> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAmAAnlXJleYiY43IUyOrGgdAaVhachb4I9ODpMQIJeJc#> .
@prefix beldoc: <http://resource.belframework.org/belframework/1.0/knowledge/small_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix mgi: <http://www.informatics.jax.org/marker/MGI:> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix mesh: <http://purl.bioontology.org/ontology/MSH/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 belv:hasSubstitution "G,12,D";
    belv:variantOf mgi:96680;
    a proteinModification: .
  
  sub:_2 occursIn: mesh:D008168, species:10090;
    rdf:object mesh:D009369;
    rdf:predicate belv:increases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "p(MGI:Kras,sub(G,12,D)) -> path(MESHD:Neoplasms)" .
}

sub:provenance {
  beldoc: dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved.";
    dce:title "BEL Framework Small Corpus Document";
    dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License";
    pav:authoredBy sub:_4;
    pav:version "1.6" .
  
  sub:_3 prov:value """Based on these observations, a mouse model of lung adenocarcinoma has been generated
in which nasal instillation of Ad-Cre to the lungs of K-Ras+/LSL-G12D  conditional
mutant mice (Figure 1a) results in the expression of oncogenic K-RasG12D
and the development of lesions that resemble human tumors (Jackson et al., 2001).""";
    prov:wasQuotedFrom pubmed:19151761 .
  
  sub:_4 rdfs:comment "support@belframework.org";
    rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:19151761;
    prov:wasDerivedFrom beldoc:, sub:_3 .
}

sub:pubinfo {
  this: dc:created "2014-07-03T14:29:32.921+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}