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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAmKEUoJezyLdy6p1fviSxdEloGKVrlRUirJSAmayPIXE#_5 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAmKEUoJezyLdy6p1fviSxdEloGKVrlRUirJSAmayPIXE#_4 http://www.w3.org/ns/prov#value When PPARg expression was restored with retroviral gene transfer, however, they differentiated well, suggesting that C/EBPa plays an important role in adipogenesis primarily by inducing the expression of PPARg. Ectopic expression of PPARg circumvents the requirement for C/EBPa in adipogenesis, at least with respect to lipid accumulation and most gene expression. 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