@prefix dcterms: . @prefix chebi: . @prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix go: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix hasAgent: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasAgent: sub:_2; a go:0003824 . sub:_2 geneProductOf: hgnc:9604; a Protein: . sub:_3 occursIn: species:9606; rdf:object chebi:15551; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "cat(p(HGNC:PTGS1)) -> a(SCHEM:Dinoprostone)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_5; pav:version "1.4" . sub:_4 prov:value "Cell-specific prostaglandin synthases convert PGH2 into a series of prostaglandins, including PGI2, PGF2alpha, PGD2 and PGE2 (Fig. 1). Fig. 1 Legend - Pathway of prostaglandin production. Arachidonic acid is liberated from membranes by phospholipase A2. The cyclooxygenase enzymes (COX-1 and COX-2) produce prostaglandin H2 (PGH2) from arachidonic acid. PGH2 is acted upon by prostaglandin synthases to produce PGI2, PGD2, PGE2 and PGF2alpha. PGD2 is metabolized to 15-deoxy-12,14-PGJ2 (15-d-PGJ2). "; prov:wasQuotedFrom pubmed:11864843 . sub:_5 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:11864843; prov:wasDerivedFrom beldoc:, sub:_4 . } sub:pubinfo { this: dcterms:created "2014-07-03T14:30:01.302+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }