@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix hgnc: . @prefix geneProductOf: . @prefix hasPart: . @prefix ProteinComplex: . @prefix go: . @prefix hasAgent: . @prefix species: . @prefix occursIn: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 hasPart: sub:_2, sub:_3; a ProteinComplex: . sub:_2 geneProductOf: hgnc:2348; a Protein: . sub:_3 geneProductOf: hgnc:2345; a Protein: . sub:_4 hasAgent: sub:_5; a go:0042789 . sub:_5 geneProductOf: hgnc:2345; a Protein: . sub:_6 occursIn: species:9606; rdf:object sub:_4; rdf:predicate belv:directlyIncreases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "complex(p(HGNC:CREBBP),p(HGNC:CREB1)) => tscript(p(HGNC:CREB1))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_8; pav:version "1.4" . sub:_7 prov:value "Moreover, PP1 was shown to act as a major CTD phosphatase in nuclear extracts and to affinity-purify with RNA polymerase II. Both PP1 and the nuclear regulator NIPP1 have also been identified as components of the Tat-associated RNA polymerase II complex, which regulates transcription from the human immunodeficiency virus type 1 promoter (40, 275). The transcription factor CREB mediates the expression of cAMP-induced genes by binding to a conserved cAMP-responsive element. Phosphorylation of CREB on Ser-133, e.g., by PKA, promotes the recruitment of the histone acetyltransferase CBP, which facilitates access of the promoter region to the transcriptional machinery."; prov:wasQuotedFrom pubmed:14715909 . sub:_8 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:14715909; prov:wasDerivedFrom beldoc:, sub:_7 . } sub:pubinfo { this: dct:created "2014-07-03T14:30:19.665+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }