@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAmphZ_QqPVGXNw0dChY5EPou-L5kf7lgjolGQoHDOXuc
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAmphZ_QqPVGXNw0dChY5EPou-L5kf7lgjolGQoHDOXuc#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix RNA: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_33697
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix mesh: <
http://purl.bioontology.org/ontology/MSH/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
geneProductOf:
hgnc:15464
;
a
RNA:
.
sub:_2
occursIn:
mesh:D015603
,
species:9606
;
rdf:object
sub:_1
;
rdf:predicate
belv:increases
;
rdf:subject
go:0030154
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"bp(GO:\"cell differentiation\") -> r(HGNC:SPINK5)" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_4
;
pav:version
"1.4" .
sub:_3
prov:value
"SPINK5, encoding the putative multi-domain serine protease inhibitor LEKTI, was recently identified as the defective gene in the severe autosomal recessive ichthyosiform skin condition, Netherton syndrome (NS). Using monoclonal and polyclonal antibodies, we show that LEKTI is a marker of epithelial differentiation, strongly expressed in the granular and uppermost spinous layers of the epidermis, and in differentiated layers of stratified epithelia. " ;
prov:wasQuotedFrom
pubmed:12915442
.
sub:_4
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:12915442
;
prov:wasDerivedFrom
beldoc:
,
sub:_3
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:15.494+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}