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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#_5 http://www.w3.org/ns/prov#value To better understand the mechanism(s) through which pRb positively affects myogenesis and to ascertain why the later steps of myogenesis are specifically altered in the absence of pRb, we have further characterized the differentiation defects that are seen in pRb-deficient muscle cells. We demonstrate that the failure to activate late muscle-gene expression in pRbdeficient myocytes is due to a requirement for both MyoD and pRb in the activation of MEF2 transactivation-domain (TAD) function. http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10322110 http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10322110 http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#_5 http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE http://purl.org/dc/terms/created 2014-07-03T14:29:47.100+02:00 http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAnRYeVDJ6H-cyaCLIOQePSMM6_rQOv9w_C1OCAHYholE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234