http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#Head http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#provenance http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://amigo.geneontology.org/amigo/term/GO:0046323 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/1.0/namespace/selventa-legacy-chemical-names/serum%20insulin http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:"serum insulin") -> bp(GO:"glucose import") http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_3 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_2 http://www.w3.org/ns/prov#value Most prominently, adenoviral gene expression of a dominant-negative PKD isoform, PKD3, primarily inhibits basal glucose uptake and, to a lesser extent, insulin-stimulated glucose uptake, whereas overexpression of wild-type PKD3 significantly enhances basal glucose uptake. Moreover, expression of a PKD3-targeted siRNA significantly inhibits basal glucose uptake. Taken together, our results indicate that PKD, specifically PKD3, directly contributes to insulin-independent basal glucose uptake in L6 skeletal muscle cells. http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/15496505 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/15496505 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#_2 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw#pubinfo http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://purl.org/dc/terms/created 2014-07-03T14:30:28.868+02:00 http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAna1tsrg49Y0B_UMz8TnSkDLacDwhEgmwTNXqmf5gyiw http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234