. . . . . . . . . . . . . . "cat(p(MGI:Irs1)) -> bp(GO:\"insulin receptor signaling pathway\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Mice lacking the IRS-1 protein are insulin resistant but do not develop overt diabetes. By contrast, animals lacking IRS-2 exhibit both impaired glucose tolerance and diabetes, which appears to result from a defect in insulin secretion as well as insulin resistance, presumably owing to decreased b-cell proliferation in the pancreas in the face of increased demand for insulin." . . "Selventa" . . . . "2014-07-03T14:30:01.091+02:00"^^ . . .