sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "1.4" .
  sub:_5 prov:value "FAK appears to play a major role in conveying survival signals from the ECM (50, 51). Because FAK binds PI 3-kinase, the protective effect against anoikis may be the result of PI 3-kinase-mediated activation of protein kinase B/Akt (52). Akt promotes survival, at least in part, by phosphorylating and thereby inactivating two proapoptotic proteins, Bad and caspase-9 (53) (Fig. 4). Inhibition of p53 prevents FAKdeficient cells from undergoing anoikis when deprived of growth factors, suggesting that p53 mediates the death signal under FAK deficiency (51)." ;
    prov:wasQuotedFrom pubmed:10446041 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:10446041 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}