. . . . . . . . . . . . . . . . "kin(p(HGNC:PTK2)) -> kin(complex(NCH:\"p85/p110 PI3Kinase Complex\"))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "FAK appears to play a major role in conveying survival signals from the ECM (50, 51). Because FAK binds PI 3-kinase, the protective effect against anoikis may be the result of PI 3-kinase-mediated activation of protein kinase B/Akt (52). Akt promotes survival, at least in part, by phosphorylating and thereby inactivating two proapoptotic proteins, Bad and caspase-9 (53) (Fig. 4). Inhibition of p53 prevents FAKdeficient cells from undergoing anoikis when deprived of growth factors, suggesting that p53 mediates the death signal under FAK deficiency (51)." . . "Selventa" . . . . "2014-07-03T14:29:48.029+02:00"^^ . . .