http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#head http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#provenance http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://rdf.disgenet.org/resource/gda/DGNc6e987acb90d982fe2cb3da99c3c92b1 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/5564 http://rdf.disgenet.org/resource/gda/DGNc6e987acb90d982fe2cb3da99c3c92b1 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0007134 http://rdf.disgenet.org/resource/gda/DGNc6e987acb90d982fe2cb3da99c3c92b1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001123 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#provenance http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://purl.org/dc/terms/description [Renal cell carcinoma (RCC) is a metabolic disease, being characterized by the dysregulation of metabolic pathways involved in oxygen sensing (VHL/HIF pathway alterations and the subsequent up-regulation of HIF-responsive genes such as VEGF, PDGF, EGF, and glucose transporters GLUT1 and GLUT4, which justify the RCC reliance on aerobic glycolysis), energy sensing (fumarate hydratase-deficient, succinate dehydrogenase-deficient RCC, mutations of HGF/MET pathway resulting in the metabolic Warburg shift marked by RCC increased dependence on aerobic glycolysis and the pentose phosphate shunt, augmented lipogenesis, and reduced AMPK and Krebs cycle activity) and/or nutrient sensing cascade (deregulation of AMPK-TSC1/2-mTOR and PI3K-Akt-mTOR pathways).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/27453294 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/dc/terms/created 2017-10-17T13:15:36+02:00 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP851366.RAnmmB07NcLfWc3YYDeFE0UxuTo04f0hUYEbvW3SuqTgk http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0