@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix mesh: . @prefix hgnc: . @prefix proteinModification: . @prefix psimod: . @prefix occursIn: . @prefix species: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 belv:variantOf hgnc:10436; a proteinModification:, psimod:00696 . sub:_2 occursIn: mesh:D018482, species:9606; rdf:object sub:_1; rdf:predicate belv:increases; rdf:subject mesh:D015444; a rdf:Statement . sub:assertion rdfs:label "bp(MESHPP:Exercise) -> p(HGNC:RPS6KB1,pmod(P))" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_4; pav:version "1.4" . sub:_3 prov:value "Recently published data have revealed rapid up-regulation of Akt activity in isolated skeletal muscle subjected to passive stretch, which appears specific to fast-twitch muscle (Sakamoto et al. 2003). The stretch-induced activation of Akt is completely blocked through pretreatment with wortmannin, an inhibitor of PI3K. In other studies phosphorylation of both 4E-BP1 and S6K1 has been shown to be enhanced in response to muscle loading (Baar & Esser, 1999; Bodine et al. 2001; Nader & Esser, 2001; Rommel et al. 2001) and positively contributes to the up-regulation of select gene expression necessary to elicit long-term increases in skeletal muscle accretion."; prov:wasQuotedFrom pubmed:15294054 . sub:_4 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:15294054; prov:wasDerivedFrom beldoc:, sub:_3 . } sub:pubinfo { this: dct:created "2014-07-03T14:30:26.520+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }