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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#_7 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#_6 http://www.w3.org/ns/prov#value FAK also combines with, and may activate, phosphoinositide 3-OH kinase (PI 3-kinase), either directly or through the Src kinase (13). Finally, there is evidence that Src phosphorylates FAK at Tyr925, creating a binding site for the complex of the adapter Grb2 and Ras guanosine 5'-triphosphate exchange factor mSOS (10). These interactions link FAK to signaling pathways that modify the cytoskeleton and activate mitogen-activated protein kinase (MAPK) cascades (Fig. 3A). http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/10446041 http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/10446041 http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#_6 http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k#pubinfo http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k http://purl.org/dc/terms/created 2014-07-03T14:29:48.012+02:00 http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAo_BRMJCCgI9cGo9pp12aTs5cOZwrl7jHfxMa0jUGN1k http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234