http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#Head http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#provenance http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.bioontology.org/ontology/MSH/D004730 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://amigo.geneontology.org/amigo/term/GO:0001525 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/decreases http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/1.0/namespace/selventa-legacy-chemical-names/Angiostatin http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:Angiostatin) -| bp(GO:angiogenesis) http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_3 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_2 http://www.w3.org/ns/prov#value Furthermore, integrin ?1?1-null mice have been shown to be deficient in tumour angiogenesis42. The reason for this is thought to be that the expression of matrix metalloproteinase (MMP)-9 is elevated in the absence of ?1?1, which normally suppresses MMP-9 expression.As a result, more angiostatin - a peptide that suppresses angiogenesis - is produced by MMP-9- catalysed proteolytic cleavage of plasminogen. So, the pathways through which these integrins affect angiogenesis might be different from those used by ?v?3,?v?5 and ?5?1. http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/12635171 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/12635171 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#_2 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI#pubinfo http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://purl.org/dc/terms/created 2014-07-03T14:30:10.924+02:00 http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAoiyvNNXbasJm2-QfYRArbR7bfnSVi7Sk7x69bs281RI http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234