. . . . . . . . . . . . . . . . "tscript(p(MGI:Pparg)) -> p(MGI:Adipoq)" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Progressive insulin resistance in MKO mice Body weights were similar in control and MKO mice at 6 and 14 months of age (Table 1). Basal glucose levels were measured every two months (data not shown); values were the same among all groups at 6 and 14 months of age (Table 1). Basal insulin levels, measured throughout the lifetime of these animals, were significantly elevated in MKOfl/fl compared with controlfl/fl mice as early as 6 months of age (P = 0.0004). There was a nonsignificant increase in basal levels of free fatty acids (FFA; 20?25%) in both MKO groups, (and these differences were amplified during the glucose clamp study) (see below). Triglyceride levels were significantly elevated in both MKO groups compared with controls (approx1.5-fold; P = 0.001) by 14 months of age (Table 1). At 14 months, the absence of one Pparg allele in the controlfl/- mice caused a significant reduction (33%; P = 0.035) in plasma Acrp-30 (adipocyte complement-related protein, 30 kDa)." . . "Selventa" . . . . "2014-07-03T14:30:18.436+02:00"^^ . . .