sub:provenance { beldoc:dce:description "Approximately 2000 hand curated statements drawn from 57 PubMeds." ; dce:rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." ; dce:title "BEL Framework Small Corpus Document" ; dc:license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" ; pav:authoredBysub:_8 ; pav:version "1.6" . sub:_7prov:value """we combined the stimulation with glucose or insulin with the cotreatment with inhibitors of the insulin receptor tyrosine kinase [hydroxy-2-naphthalenylmethylphosphonic acid trisacetoxymethyl ester (HNMPA)], PI 3-kinase (wortmannin and LY294002), and mTOR (rapamycin). As shown in Figs. 1 and 2, HNMPA, wortmannin, LY294002, and rapamycin inhibited both glucose- and insulin-stimulated insulin biosynthesis in both human pancreatic islets and RIN β-cells.""" ; prov:wasQuotedFrompubmed:15001544 . sub:_8rdfs:comment "support@belframework.org" ; rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:15001544 ; prov:wasDerivedFrombeldoc: , sub:_7 . }