@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RApTtSkWQ-S-R_x1rSGCSl0amwO6mNASuJhwB_3b5Fy7c
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RApTtSkWQ-S-R_x1rSGCSl0amwO6mNASuJhwB_3b5Fy7c#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0042789
.
sub:_2
geneProductOf:
hgnc:7105
;
a
Protein:
.
sub:_3
hasAgent:
sub:_4
;
a
go:0042789
.
sub:_4
geneProductOf:
hgnc:4910
;
a
Protein:
.
sub:_5
occursIn:
species:9606
;
rdf:object
sub:_3
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"tscript(p(HGNC:MITF)) -> tscript(p(HGNC:HIF1A))" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_7
;
pav:version
"1.4" .
sub:_6
prov:value
"melanocyte-specific transcription factor, microphthalmia-associated transcription factor (MITF), binds to the Hif1a promoter and strongly stimulates its transcriptional activity. Further, MITF \\\"silencing\\\" abrogates the cAMP effect on Hif1a expression, and overexpression of MITF in human melanoma cells is sufficient to stimulate HIF1A mRNA" ;
prov:wasQuotedFrom
pubmed:15983061
.
sub:_7
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:15983061
;
prov:wasDerivedFrom
beldoc:
,
sub:_6
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:36.212+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}