. . . . . . . . . . . "p(HGNC:PTEN) -| a(SCHEM:\"Phosphatidylinositol-3,4,5-trisphosphate\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Activity of this pathway is also determined by phosphatidylinositol- 3-phosphates such as phosphatase and tensin homologue43 and the SH2 domain-containing inositol-5-phosphatase SHIP2 (ref. 44). Overexpression of these enzymes leads to decreased levels of PtdIns(3,4,5)P3. This might terminate signal transduction and/or change the nature of the phosphoinositides, altering the binding specificity to PH or phox homology domains." . . "Selventa" . . . . "2014-07-03T14:29:59.604+02:00"^^ . . .