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a(CHEBI:estradiol) -> p(HGNC:MAPK9,pmod(P))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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1.4
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After 12 h of treatment, both prolactin and estradiol modestly increased JNK1/2 phosphorylation in prolactin deficient MCF7 cells. After 24 h, phosphorylated JNK1/2 was elevated in the vehicle treated control. Consistent with elevation of phospho JNK1/2 at 12 h, E2 in particular, increased levels of phosphorylated c-JUN (ser63), a JNK target. Total levels of c-JUN were slightly increased by both hormones individually, with no further increase by both hormones together after both 12 and 24 h of treatment.
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Selventa
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2014-07-03T14:30:33.268+02:00
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