@prefix chebi: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=
> .
@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAqXNuFOqLzpOzHDoDfgCTM2-3E5ka82ynRlNiGentfUY
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAqXNuFOqLzpOzHDoDfgCTM2-3E5ka82ynRlNiGentfUY#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix hasPart: <
http://purl.obolibrary.org/obo/BFO_0000051
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix mgi: <
http://www.informatics.jax.org/marker/MGI:
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix ProteinComplex: <
http://amigo.geneontology.org/amigo/term/GO:0043234
> .
@prefix ncm: <
http://resource.belframework.org/belframework/1.0/namespace/selventa-named-mouse-complexes/
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
ncm:Interleukin%204%20Receptor%20Complex
a
ProteinComplex:
.
sub:_1
hasPart:
chebi:9168
,
sub:_2
;
a
ProteinComplex:
.
sub:_2
geneProductOf:
mgi:95541
;
a
Protein:
.
sub:_3
occursIn:
species:10090
;
rdf:object
ncm:Interleukin%204%20Receptor%20Complex
;
rdf:predicate
belv:decreases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"complex(a(SCHEM:Sirolimus),p(MGI:Fkbp1a)) -| complex(NCM:\"Interleukin 4 Receptor Complex\")" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_5
;
pav:version
"1.4" .
sub:_4
prov:value
"RAPA suppresses the functional activation of dendritic cells (DCs) both in vitro and in vivo.In vitro, RAPA inhibits IL-4-dependent maturation and T-cell stimulatory activity of murine bone marrow-derived DCs. These effects are associated with posttranscriptional down-regulation of both subunits of the IL-4 receptor complex (CD124, CD132) and are mediated via binding of RAPA to its intracellular receptor FK506-binding protein 12 (FKBP12)." ;
prov:wasQuotedFrom
pubmed:12531798
.
sub:_5
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:12531798
;
prov:wasDerivedFrom
beldoc:
,
sub:_4
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:30:09.452+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}