. . . . . . . . . . . . . . . "complex(a(SCHEM:Sirolimus),p(MGI:Fkbp1a)) -| complex(NCM:\"Interleukin 4 Receptor Complex\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "RAPA suppresses the functional activation of dendritic cells (DCs) both in vitro and in vivo.In vitro, RAPA inhibits IL-4-dependent maturation and T-cell stimulatory activity of murine bone marrow-derived DCs. These effects are associated with posttranscriptional down-regulation of both subunits of the IL-4 receptor complex (CD124, CD132) and are mediated via binding of RAPA to its intracellular receptor FK506-binding protein 12 (FKBP12)." . . "Selventa" . . . . "2014-07-03T14:30:09.452+02:00"^^ . . .