http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#Head http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://www.nanopub.org/nschema#hasAssertion http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#assertion http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://www.nanopub.org/nschema#hasProvenance http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#provenance http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://www.nanopub.org/nschema#hasPublicationInfo http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#pubinfo http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#assertion https://w3id.org/biolink/vocab/FDA_adverse_event_level http://www.w3.org/2000/01/rdf-schema#label FDA adverse event level - https://w3id.org/biolink/vocab/FDA_approval_status http://www.w3.org/2000/01/rdf-schema#label FDA approval status - https://w3id.org/biolink/vocab/actively_involved_in http://www.w3.org/2000/01/rdf-schema#label actively involved in - holds between a continuant and a process or function, where the continuant actively contributes to part or all of the process or function it realizes https://w3id.org/biolink/vocab/address http://www.w3.org/2000/01/rdf-schema#label address - the particulars of the place where someone or an organization is situated. For now, this slot is a simple text "blob" containing all relevant details of the given location for fitness of purpose. For the moment, this "address" can include other contact details such as email and phone number(?). https://w3id.org/biolink/vocab/adjusted_p_value http://www.w3.org/2000/01/rdf-schema#label adjusted p value - The adjusted p-value is the probability of obtaining test results at least as extreme as the results actually observed, under the assumption that the null hypothesis is correct, adjusted for multiple comparisons. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<. https://w3id.org/biolink/vocab/affected_by http://www.w3.org/2000/01/rdf-schema#label affected by - describes an entity of which the state or quality is affected by another existing entity. https://w3id.org/biolink/vocab/affects http://www.w3.org/2000/01/rdf-schema#label affects - describes an entity that has a direct affect on the state or quality of another existing entity. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects risk for' and 'prevents, where the outcome is something that may or may not come to be. https://w3id.org/biolink/vocab/affects_risk_for http://www.w3.org/2000/01/rdf-schema#label affects risk for - holds between two entities where exposure to one entity alters the chance of developing the other https://w3id.org/biolink/vocab/affiliation http://www.w3.org/2000/01/rdf-schema#label affiliation - a professional relationship between one provider (often a person) within another provider (often an organization). Target provider identity should be specified by a CURIE. Providers may have multiple affiliations. https://w3id.org/biolink/vocab/agent_id http://www.w3.org/2000/01/rdf-schema#label agent id - Different classes of agents have distinct preferred identifiers. For publishers, use the ISBN publisher code. See https://grp.isbn-international.org/ for publisher code lookups. For editors, authors and individual providers, use the individual's ORCID if available; Otherwise, a ScopusID, ResearchID or Google Scholar ID ('GSID') may be used if the author ORCID is unknown. Institutional agents could be identified by an International Standard Name Identifier ('ISNI') code. https://w3id.org/biolink/vocab/agent_name http://www.w3.org/2000/01/rdf-schema#label agent name - it is recommended that an author's 'name' property be formatted as "surname, firstname initial." https://w3id.org/biolink/vocab/aggregator_knowledge_source http://www.w3.org/2000/01/rdf-schema#label aggregator knowledge source - An intermediate aggregator resource from which knowledge expressed in an Association was retrieved downstream of the original source, on its path to its current serialized form. https://w3id.org/biolink/vocab/ameliorates http://www.w3.org/2000/01/rdf-schema#label ameliorates - A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure, clinical intervention) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition. https://w3id.org/biolink/vocab/anatomical_context_qualifier http://www.w3.org/2000/01/rdf-schema#label anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location). https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_association_object http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_association_subject http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_ontogenic_association_object http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity ontogenic association object - the structure at an earlier time https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_ontogenic_association_predicate http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity ontogenic association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_ontogenic_association_subject http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity ontogenic association subject - the structure at a later time https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_part_of_association_object http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity part of association object - the whole https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_part_of_association_predicate http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity part of association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/anatomical_entity_to_anatomical_entity_part_of_association_subject http://www.w3.org/2000/01/rdf-schema#label anatomical entity to anatomical entity part of association subject - the part https://w3id.org/biolink/vocab/animal_model_available_from http://www.w3.org/2000/01/rdf-schema#label animal model available from - https://w3id.org/biolink/vocab/article_iso_abbreviation http://www.w3.org/2000/01/rdf-schema#label article iso abbreviation - Optional value, if used locally as a convenience, is set to the iso abbreviation of the 'published in' parent. https://w3id.org/biolink/vocab/article_published_in http://www.w3.org/2000/01/rdf-schema#label article published in - The enclosing parent serial containing the article should have industry-standard identifier from ISSN. https://w3id.org/biolink/vocab/aspect_qualifier http://www.w3.org/2000/01/rdf-schema#label aspect qualifier - Composes with the core concept to describe new concepts of a different ontological type. e.g. a process in which the core concept participates, a function/activity/role held by the core concept, or a characteristic/quality that inheres in the core concept. The purpose of the aspect slot is to indicate what aspect is being affected in an 'affects' association. https://w3id.org/biolink/vocab/assesses http://www.w3.org/2000/01/rdf-schema#label assesses - The effect of a thing on a target was interrogated in some assay. A relationship between some perturbing agent (usually a chemical compound) and some target entity, where the affect of the perturbing agent on the target entity was interrogated in a particular assay. The target might be a particular protein, tissue, phenotype, whole organism, cell line, or other type of biological entity. https://w3id.org/biolink/vocab/associated_environmental_context http://www.w3.org/2000/01/rdf-schema#label associated environmental context - An attribute that can be applied to an association where the association holds between two entities located or occurring in a particular environment. For example, two microbial taxa may interact in the context of a human gut; a disease may give rise to a particular phenotype in a particular environmental exposure. # TODO: add examples of values for this property. https://w3id.org/biolink/vocab/associated_with http://www.w3.org/2000/01/rdf-schema#label associated with - Expresses a relationship between two named things where the relationship is typically generated statistically (though not in all cases), and is weaker than its child, 'correlated with', but stronger than its parent, 'related to'. This relationship holds between two concepts represented by variables for which a statistical dependence is demonstrated. E.g. the statement “Atrial Fibrillation (Afib) is associated with Myocardial Infarction (MI)” asserts that having Afib is not statistically independent from whether a patient will also have MI. Note that in Translator associations, the subject and object concepts may map exactly to the statistical variables, or represent related entities for which the variables serve as proxies in an Association (e.g. diseases, chemical entities or processes). https://w3id.org/biolink/vocab/associated_with_decreased_likelihood_of http://www.w3.org/2000/01/rdf-schema#label associated with decreased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is less probable. https://w3id.org/biolink/vocab/associated_with_increased_likelihood_of http://www.w3.org/2000/01/rdf-schema#label associated with increased likelihood of - Expresses a relationship between two named things where the relationship is typically generated statistically and the state or fact of something is more probable. https://w3id.org/biolink/vocab/associated_with_likelihood_of http://www.w3.org/2000/01/rdf-schema#label associated with likelihood of - A a relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated, wherein the state or value of one variable predicts the future state or value of the other. E.g. the statement “An Atrial Fibrillation (Afib) diagnosis is associated with likelihood of a Myocardial Infarction (MI) diagnosis” asserts that the state of having Afib is associated with an increased or decreased likelihood that a patient will later exhibit MI. https://w3id.org/biolink/vocab/associated_with_resistance_to http://www.w3.org/2000/01/rdf-schema#label associated with resistance to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of resistance to treatment by the chemical. https://w3id.org/biolink/vocab/associated_with_sensitivity_to http://www.w3.org/2000/01/rdf-schema#label associated with sensitivity to - A relation that holds between a named thing and a chemical that specifies that the change in the named thing is found to be associated with the degree of sensitivity to treatment by the chemical. https://w3id.org/biolink/vocab/association_category http://www.w3.org/2000/01/rdf-schema#label association category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. * In a neo4j database this MAY correspond to the neo4j label tag. * In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ... In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} https://w3id.org/biolink/vocab/association_slot http://www.w3.org/2000/01/rdf-schema#label association slot - any slot that relates an association to another entity https://w3id.org/biolink/vocab/association_type http://www.w3.org/2000/01/rdf-schema#label association type - rdf:type of biolink:Association should be fixed at rdf:Statement https://w3id.org/biolink/vocab/attribute_name http://www.w3.org/2000/01/rdf-schema#label attribute name - The human-readable 'attribute name' can be set to a string which reflects its context of interpretation, e.g. SEPIO evidence/provenance/confidence annotation or it can default to the name associated with the 'has attribute type' slot ontology term. https://w3id.org/biolink/vocab/author http://www.w3.org/2000/01/rdf-schema#label author - an instance of one (co-)creator primarily responsible for a written work https://w3id.org/biolink/vocab/authors http://www.w3.org/2000/01/rdf-schema#label authors - connects an publication to the list of authors who contributed to the publication. This property should be a comma-delimited list of author names. It is recommended that an author's name be formatted as "surname, firstname initial.". Note that this property is a node annotation expressing the citation list of authorship which might typically otherwise be more completely documented in biolink:PublicationToProviderAssociation defined edges which point to full details about an author and possibly, some qualifiers which clarify the specific status of a given author in the publication. https://w3id.org/biolink/vocab/available_from http://www.w3.org/2000/01/rdf-schema#label available from - https://w3id.org/biolink/vocab/base_coordinate http://www.w3.org/2000/01/rdf-schema#label base coordinate - A position in the base coordinate system. Base coordinates start at position 1 instead of position 0. https://w3id.org/biolink/vocab/behavior_to_behavioral_feature_association_object http://www.w3.org/2000/01/rdf-schema#label behavior to behavioral feature association object - behavioral feature that is the object of the association https://w3id.org/biolink/vocab/behavior_to_behavioral_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label behavior to behavioral feature association subject - behavior that is the subject of the association https://w3id.org/biolink/vocab/binds http://www.w3.org/2000/01/rdf-schema#label binds - A causal mechanism mediated by the direct contact between effector and target chemical or biomolecular entity, which form a stable physical interaction. https://w3id.org/biolink/vocab/biological_role_mixin http://www.w3.org/2000/01/rdf-schema#label biological role mixin - A role played by the chemical entity or part thereof within a biological context. https://w3id.org/biolink/vocab/biomarker_for http://www.w3.org/2000/01/rdf-schema#label biomarker for - holds between a measurable chemical entity and a disease or phenotypic feature, where the entity is used as an indicator of the presence or state of the disease or feature. https://w3id.org/biolink/vocab/bonferonni_adjusted_p_value http://www.w3.org/2000/01/rdf-schema#label bonferonni adjusted p value - The Bonferroni correction is an adjustment made to P values when several dependent or independent statistical tests are being performed simultaneously on a single data set. To perform a Bonferroni correction, divide the critical P value (α) by the number of comparisons being made. P is always italicized and capitalized. The actual P value* should be expressed (P=. 04) rather than expressing a statement of inequality (P<. 05), unless P<. https://w3id.org/biolink/vocab/book_chapter_published_in http://www.w3.org/2000/01/rdf-schema#label book chapter published in - The enclosing parent book containing the chapter should have industry-standard identifier from ISBN. https://w3id.org/biolink/vocab/book_id http://www.w3.org/2000/01/rdf-schema#label book id - Books should have industry-standard identifier such as from ISBN. https://w3id.org/biolink/vocab/book_type http://www.w3.org/2000/01/rdf-schema#label book type - Should generally be set to an ontology class defined term for 'book'. https://w3id.org/biolink/vocab/broad_match http://www.w3.org/2000/01/rdf-schema#label broad match - a list of terms from different schemas or terminology systems that have a broader, more general meaning. Broader terms are typically shown as parents in a hierarchy or tree. https://w3id.org/biolink/vocab/broad_matches http://www.w3.org/2000/01/rdf-schema#label broad matches - A list of terms from different schemas or terminology systems that have a broader meaning. Such terms often describe a more general concept from different ontological perspectives. https://w3id.org/biolink/vocab/capable_of http://www.w3.org/2000/01/rdf-schema#label capable of - holds between a physical entity and process or function, where the continuant alone has the ability to carry out the process or function. https://w3id.org/biolink/vocab/case_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label case to entity association mixin subject - the case (e.g. patient) that has the property https://w3id.org/biolink/vocab/catalyst_qualifier http://www.w3.org/2000/01/rdf-schema#label catalyst qualifier - a qualifier that connects an association between two causally connected entities (for example, two chemical entities, or a chemical entity in that changes location) and the gene product, gene, or complex that enables or catalyzes the change. https://w3id.org/biolink/vocab/category http://www.w3.org/2000/01/rdf-schema#label category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. * In a neo4j database this MAY correspond to the neo4j label tag. * In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ... In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} https://w3id.org/biolink/vocab/causal_mechanism_qualifier http://www.w3.org/2000/01/rdf-schema#label causal mechanism qualifier - A statement qualifier representing a type of molecular control mechanism through which an effect of a chemical on a gene or gene product is mediated (e.g. 'agonism', 'inhibition', 'allosteric modulation', 'channel blocker') https://w3id.org/biolink/vocab/caused_by http://www.w3.org/2000/01/rdf-schema#label caused by - holds between two entities where the occurrence, existence, or activity of one is caused by the occurrence or generation of the other https://w3id.org/biolink/vocab/causes http://www.w3.org/2000/01/rdf-schema#label causes - holds between two entities where the occurrence, existence, or activity of one causes the occurrence or generation of the other https://w3id.org/biolink/vocab/cell_line_as_a_model_of_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label cell line as a model of disease association subject - A cell line derived from an organismal entity with a disease state that is used as a model of that disease. https://w3id.org/biolink/vocab/cell_line_to_disease_or_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label cell line to disease or phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/cell_line_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label cell line to entity association mixin subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chapter http://www.w3.org/2000/01/rdf-schema#label chapter - chapter of a book https://w3id.org/biolink/vocab/chemical_affects_gene_association_anatomical_context_qualifier http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location). https://w3id.org/biolink/vocab/chemical_affects_gene_association_causal_mechanism_qualifier http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association causal mechanism qualifier - A statement qualifier representing a type of molecular control mechanism through which an effect of a chemical on a gene or gene product is mediated (e.g. 'agonism', 'inhibition', 'allosteric modulation', 'channel blocker') https://w3id.org/biolink/vocab/chemical_affects_gene_association_object http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_affects_gene_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_affects_gene_association_qualified_predicate http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association qualified predicate - Predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading. This qualifier holds a relationship to be used instead of that expressed by the primary predicate, in a ‘full statement’ reading of the association, where qualifier-based semantics are included. This is necessary only in cases where the primary predicate does not work in a full statement reading. https://w3id.org/biolink/vocab/chemical_affects_gene_association_species_context_qualifier http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association species context qualifier - A statement qualifier representing a taxonomic category of species in which a relationship expressed in an association took place. https://w3id.org/biolink/vocab/chemical_affects_gene_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical affects gene association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_entity_assesses_named_thing_association_object http://www.w3.org/2000/01/rdf-schema#label chemical entity assesses named thing association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_entity_assesses_named_thing_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical entity assesses named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_entity_assesses_named_thing_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical entity assesses named thing association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_entity_or_gene_or_gene_product_regulates_gene_association_object http://www.w3.org/2000/01/rdf-schema#label chemical entity or gene or gene product regulates gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_entity_or_gene_or_gene_product_regulates_gene_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical entity or gene or gene product regulates gene association predicate - the direction is always from regulator to regulated https://w3id.org/biolink/vocab/chemical_entity_or_gene_or_gene_product_regulates_gene_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical entity or gene or gene product regulates gene association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_entity_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label chemical entity to entity association mixin subject - the chemical entity that is an interactor https://w3id.org/biolink/vocab/chemical_gene_interaction_association_anatomical_context_qualifier http://www.w3.org/2000/01/rdf-schema#label chemical gene interaction association anatomical context qualifier - A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or sub-cellular location). https://w3id.org/biolink/vocab/chemical_gene_interaction_association_object http://www.w3.org/2000/01/rdf-schema#label chemical gene interaction association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_gene_interaction_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical gene interaction association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_gene_interaction_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical gene interaction association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/chemical_or_drug_or_treatment_side_effect_disease_or_phenotypic_feature_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical or drug or treatment side effect disease or phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_or_drug_or_treatment_to_disease_or_phenotypic_feature_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical or drug or treatment to disease or phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_role_mixin http://www.w3.org/2000/01/rdf-schema#label chemical role mixin - A role played by the chemical entity or part thereof within a chemical context. https://w3id.org/biolink/vocab/chemical_to_chemical_association_object http://www.w3.org/2000/01/rdf-schema#label chemical to chemical association object - the chemical element that is the target of the statement https://w3id.org/biolink/vocab/chemical_to_chemical_derivation_association_catalyst_qualifier http://www.w3.org/2000/01/rdf-schema#label chemical to chemical derivation association catalyst qualifier - this connects the derivation edge to the chemical entity that catalyzes the reaction that causes the subject chemical to transform into the object chemical. https://w3id.org/biolink/vocab/chemical_to_chemical_derivation_association_object http://www.w3.org/2000/01/rdf-schema#label chemical to chemical derivation association object - the downstream chemical entity https://w3id.org/biolink/vocab/chemical_to_chemical_derivation_association_predicate http://www.w3.org/2000/01/rdf-schema#label chemical to chemical derivation association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/chemical_to_chemical_derivation_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical to chemical derivation association subject - the upstream chemical entity https://w3id.org/biolink/vocab/chemical_to_disease_or_phenotypic_feature_association_object http://www.w3.org/2000/01/rdf-schema#label chemical to disease or phenotypic feature association object - the disease or phenotype that is affected by the chemical https://w3id.org/biolink/vocab/chemical_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label chemical to entity association mixin subject - the chemical entity or entity that is an interactor https://w3id.org/biolink/vocab/chemical_to_pathway_association_object http://www.w3.org/2000/01/rdf-schema#label chemical to pathway association object - the pathway that is affected by the chemical https://w3id.org/biolink/vocab/chemical_to_pathway_association_subject http://www.w3.org/2000/01/rdf-schema#label chemical to pathway association subject - the chemical entity that is affecting the pathway https://w3id.org/biolink/vocab/chemically_similar_to http://www.w3.org/2000/01/rdf-schema#label chemically similar to - holds between one small molecule entity and another that it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity. https://w3id.org/biolink/vocab/chi_squared_statistic http://www.w3.org/2000/01/rdf-schema#label chi squared statistic - represents the chi-squared statistic computed from observations https://w3id.org/biolink/vocab/clinical_finding_has_attribute http://www.w3.org/2000/01/rdf-schema#label clinical finding has attribute - connects any entity to an attribute https://w3id.org/biolink/vocab/clinical_measurement_has_attribute_type http://www.w3.org/2000/01/rdf-schema#label clinical measurement has attribute type - connects an attribute to a class that describes it https://w3id.org/biolink/vocab/clinical_modifier_qualifier http://www.w3.org/2000/01/rdf-schema#label clinical modifier qualifier - the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. https://w3id.org/biolink/vocab/close_match http://www.w3.org/2000/01/rdf-schema#label close match - a list of terms from different schemas or terminology systems that have a semantically similar but not strictly equivalent, broader, or narrower meaning. Such terms often describe the same general concept from different ontological perspectives (e.g. drug as a type of chemical entity versus drug as a type of role borne by a chemical entity). https://w3id.org/biolink/vocab/coexists_with http://www.w3.org/2000/01/rdf-schema#label coexists with - holds between two entities that are co-located in the same aggregate object, process, or spatio-temporal region https://w3id.org/biolink/vocab/coexpressed_with http://www.w3.org/2000/01/rdf-schema#label coexpressed with - holds between any two genes or gene products, in which both are generally expressed within a single defined experimental context. https://w3id.org/biolink/vocab/colocalizes_with http://www.w3.org/2000/01/rdf-schema#label colocalizes with - holds between two entities that are observed to be located in the same place. https://w3id.org/biolink/vocab/composed_primarily_of http://www.w3.org/2000/01/rdf-schema#label composed primarily of - x composed_primarily_of_y if:more than half of the mass of x is made from parts of y. https://w3id.org/biolink/vocab/concept_count_object http://www.w3.org/2000/01/rdf-schema#label concept count object - The number of instances in a dataset/cohort whose records contain the concept in the object slot of an association. https://w3id.org/biolink/vocab/concept_count_subject http://www.w3.org/2000/01/rdf-schema#label concept count subject - The number of instances in a dataset/cohort whose records contain the concept in the subject slot of an association. https://w3id.org/biolink/vocab/concept_pair_count http://www.w3.org/2000/01/rdf-schema#label concept pair count - The number of instances in a dataset/cohort whose records contain both the subject and object concept of an association. https://w3id.org/biolink/vocab/condition_associated_with_gene http://www.w3.org/2000/01/rdf-schema#label condition associated with gene - holds between a gene and a disease or phenotypic feature that may be influenced, contribute to, or be correlated with the gene or its alleles/products https://w3id.org/biolink/vocab/context_qualifier http://www.w3.org/2000/01/rdf-schema#label context qualifier - Restricts the setting/context/location where the core concept (or qualified core concept) resides or occurs. https://w3id.org/biolink/vocab/contraindicated_for http://www.w3.org/2000/01/rdf-schema#label contraindicated for - Holds between a drug and a disease or phenotype, such that a person with that disease should not be treated with the drug. https://w3id.org/biolink/vocab/contributes_to http://www.w3.org/2000/01/rdf-schema#label contributes to - holds between two entities where the occurrence, existence, or activity of one causes or contributes to the occurrence or generation of the other https://w3id.org/biolink/vocab/contributor_association_object http://www.w3.org/2000/01/rdf-schema#label contributor association object - agent helping to realise the given entity (e.g. such as a publication) https://w3id.org/biolink/vocab/contributor_association_predicate http://www.w3.org/2000/01/rdf-schema#label contributor association predicate - generally one of the predicate values 'provider', 'publisher', 'editor' or 'author' https://w3id.org/biolink/vocab/contributor_association_qualifiers http://www.w3.org/2000/01/rdf-schema#label contributor association qualifiers - this field can be used to annotate special characteristics of an agent relationship, such as the fact that a given author agent of a publication is the 'corresponding author' https://w3id.org/biolink/vocab/contributor_association_subject http://www.w3.org/2000/01/rdf-schema#label contributor association subject - information content entity which an agent has helped realise https://w3id.org/biolink/vocab/correlated_with http://www.w3.org/2000/01/rdf-schema#label correlated with - A relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated using a correlation analysis method. https://w3id.org/biolink/vocab/creation_date http://www.w3.org/2000/01/rdf-schema#label creation date - date on which an entity was created. This can be applied to nodes or edges https://w3id.org/biolink/vocab/decreased_likelihood_associated_with http://www.w3.org/2000/01/rdf-schema#label decreased likelihood associated with - https://w3id.org/biolink/vocab/decreases_amount_or_activity_of http://www.w3.org/2000/01/rdf-schema#label decreases amount or activity of - A grouping mixin to help with searching for all the predicates that decrease the amount or activity of the object. https://w3id.org/biolink/vocab/decreases_response_to http://www.w3.org/2000/01/rdf-schema#label decreases response to - holds between two chemical entities where the action or effect of one decreases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other https://w3id.org/biolink/vocab/derivative_qualifier http://www.w3.org/2000/01/rdf-schema#label derivative qualifier - A qualifier that composes with a core subject/object concept to describe something that is derived from the core concept. For example, the qualifier ‘metabolite’ combines with a ‘Chemical X’ core concept to express the composed concept ‘a metabolite of Chemical X’. https://w3id.org/biolink/vocab/derives_from http://www.w3.org/2000/01/rdf-schema#label derives from - holds between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity https://w3id.org/biolink/vocab/derives_into http://www.w3.org/2000/01/rdf-schema#label derives into - holds between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity https://w3id.org/biolink/vocab/description http://www.w3.org/2000/01/rdf-schema#label description - a human-readable description of an entity https://w3id.org/biolink/vocab/diagnoses http://www.w3.org/2000/01/rdf-schema#label diagnoses - a relationship that identifies the nature of (an illness or other problem) by examination of the symptoms. https://w3id.org/biolink/vocab/direction_qualifier http://www.w3.org/2000/01/rdf-schema#label direction qualifier - Composes with the core concept (+ aspect if provided) to describe a change in its direction or degree. https://w3id.org/biolink/vocab/directly_physically_interacts_with http://www.w3.org/2000/01/rdf-schema#label directly physically interacts with - A causal mechanism mediated by a direct contact between the effector and target entities (this contact may be weak or strong, transient or stable). https://w3id.org/biolink/vocab/disease_has_basis_in http://www.w3.org/2000/01/rdf-schema#label disease has basis in - A relation that holds between a disease and an entity where the state of the entity has contribution to the disease. https://w3id.org/biolink/vocab/disease_has_location http://www.w3.org/2000/01/rdf-schema#label disease has location - A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity. https://w3id.org/biolink/vocab/disease_or_phenotypic_feature_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label disease or phenotypic feature to entity association mixin subject - disease or phenotype https://w3id.org/biolink/vocab/disease_or_phenotypic_feature_to_genetic_inheritance_association_object http://www.w3.org/2000/01/rdf-schema#label disease or phenotypic feature to genetic inheritance association object - genetic inheritance associated with the specified disease or phenotypic feature. https://w3id.org/biolink/vocab/disease_or_phenotypic_feature_to_genetic_inheritance_association_predicate http://www.w3.org/2000/01/rdf-schema#label disease or phenotypic feature to genetic inheritance association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/disease_or_phenotypic_feature_to_location_association_object http://www.w3.org/2000/01/rdf-schema#label disease or phenotypic feature to location association object - anatomical entity in which the disease or feature is found. https://w3id.org/biolink/vocab/disease_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label disease to entity association mixin subject - disease class https://w3id.org/biolink/vocab/disease_to_phenotypic_feature_association_object http://www.w3.org/2000/01/rdf-schema#label disease to phenotypic feature association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/disease_to_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label disease to phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/disrupted_by http://www.w3.org/2000/01/rdf-schema#label disrupted by - describes a relationship where the structure, function, or occurrence of one entity is degraded or interfered with by another. https://w3id.org/biolink/vocab/disrupts http://www.w3.org/2000/01/rdf-schema#label disrupts - describes a relationship where one entity degrades or interferes with the structure, function, or occurrence of another. https://w3id.org/biolink/vocab/drug_regulatory_status_world_wide http://www.w3.org/2000/01/rdf-schema#label drug regulatory status world wide - An agglomeration of drug regulatory status worldwide. Not specific to FDA. https://w3id.org/biolink/vocab/drug_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label drug to entity association mixin subject - the drug that is an interactor https://w3id.org/biolink/vocab/drug_to_gene_association_object http://www.w3.org/2000/01/rdf-schema#label drug to gene association object - the gene or gene product that is affected by the drug https://w3id.org/biolink/vocab/druggable_gene_to_disease_association_has_evidence http://www.w3.org/2000/01/rdf-schema#label druggable gene to disease association has evidence - connects an association to an instance of supporting evidence https://w3id.org/biolink/vocab/druggable_gene_to_disease_association_predicate http://www.w3.org/2000/01/rdf-schema#label druggable gene to disease association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/druggable_gene_to_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label druggable gene to disease association subject - gene in which variation is correlated with the disease in a protective manner, or if the product produced by the gene can be targeted by a small molecule and this leads to a protective or improving disease state. https://w3id.org/biolink/vocab/editor http://www.w3.org/2000/01/rdf-schema#label editor - editor of a compiled work such as a book or a periodical (newspaper or an academic journal). Note that in the case of publications which have a containing "published in" node property, the editor association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the editorial agent of the encompassing publication (e.g. only from the Book referenced by the 'published_in' property of a book chapter Publication node). https://w3id.org/biolink/vocab/enabled_by http://www.w3.org/2000/01/rdf-schema#label enabled by - holds between a process and a physical entity, where the physical entity executes the process https://w3id.org/biolink/vocab/enables http://www.w3.org/2000/01/rdf-schema#label enables - holds between a physical entity and a process, where the physical entity executes the process https://w3id.org/biolink/vocab/end_coordinate http://www.w3.org/2000/01/rdf-schema#label end coordinate - The position at which the subject genomic entity ends on the chromosome or other entity to which it is located on. https://w3id.org/biolink/vocab/end_interbase_coordinate http://www.w3.org/2000/01/rdf-schema#label end interbase coordinate - The position at which the subject nucleic acid entity ends on the chromosome or other entity to which it is located on. https://w3id.org/biolink/vocab/entity_to_disease_association_mixin_object http://www.w3.org/2000/01/rdf-schema#label entity to disease association mixin object - disease https://w3id.org/biolink/vocab/entity_to_disease_or_phenotypic_feature_association_mixin_object http://www.w3.org/2000/01/rdf-schema#label entity to disease or phenotypic feature association mixin object - disease or phenotype https://w3id.org/biolink/vocab/entity_to_exposure_event_association_mixin_object http://www.w3.org/2000/01/rdf-schema#label entity to exposure event association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/entity_to_outcome_association_mixin_object http://www.w3.org/2000/01/rdf-schema#label entity to outcome association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/entity_to_phenotypic_feature_association_mixin_object http://www.w3.org/2000/01/rdf-schema#label entity to phenotypic feature association mixin object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/evidence_count http://www.w3.org/2000/01/rdf-schema#label evidence count - The number of evidence instances that are connected to an association. https://w3id.org/biolink/vocab/exacerbates http://www.w3.org/2000/01/rdf-schema#label exacerbates - A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition. https://w3id.org/biolink/vocab/exact_match http://www.w3.org/2000/01/rdf-schema#label exact match - holds between two entities that have strictly equivalent meanings, with a high degree of confidence https://w3id.org/biolink/vocab/exact_matches http://www.w3.org/2000/01/rdf-schema#label exact matches - A list of terms from different schemas or terminology systems that have an identical meaning. Such terms often describe the same concept from different ontological perspectives. https://w3id.org/biolink/vocab/exon_to_transcript_relationship_object http://www.w3.org/2000/01/rdf-schema#label exon to transcript relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/exon_to_transcript_relationship_subject http://www.w3.org/2000/01/rdf-schema#label exon to transcript relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/expected_count http://www.w3.org/2000/01/rdf-schema#label expected count - The expected (calculated) number of instances in a dataset/cohort whose records contain both the subject and object concept of an association if the subject and object concepts are independent. https://w3id.org/biolink/vocab/exposure_event_to_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label exposure event to phenotypic feature association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/expressed_in http://www.w3.org/2000/01/rdf-schema#label expressed in - holds between a gene or gene product and an anatomical entity in which it is expressed https://w3id.org/biolink/vocab/expresses http://www.w3.org/2000/01/rdf-schema#label expresses - holds between an anatomical entity and gene or gene product that is expressed there https://w3id.org/biolink/vocab/expression_site http://www.w3.org/2000/01/rdf-schema#label expression site - location in which gene or protein expression takes place. May be cell, tissue, or organ. https://w3id.org/biolink/vocab/extraction_confidence_score http://www.w3.org/2000/01/rdf-schema#label extraction confidence score - A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. https://w3id.org/biolink/vocab/food_component_of http://www.w3.org/2000/01/rdf-schema#label food component of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive) https://w3id.org/biolink/vocab/form_or_variant_qualifier http://www.w3.org/2000/01/rdf-schema#label form or variant qualifier - A qualifier that composes with a core subject/object concept to define a specific type, variant, alternative version of this concept. The composed concept remains a subtype or instance of the core concept. For example, the qualifier ‘mutation’ combines with the core concept ‘Gene X’ to express the compose concept ‘a mutation of Gene X’. https://w3id.org/biolink/vocab/frequency_qualifier http://www.w3.org/2000/01/rdf-schema#label frequency qualifier - a qualifier used in a phenotypic association to state how frequent the phenotype is observed in the subject https://w3id.org/biolink/vocab/full_name http://www.w3.org/2000/01/rdf-schema#label full name - a long-form human readable name for a thing https://w3id.org/biolink/vocab/functional_association_object http://www.w3.org/2000/01/rdf-schema#label functional association object - class describing the activity, process or localization of the gene product https://w3id.org/biolink/vocab/functional_association_subject http://www.w3.org/2000/01/rdf-schema#label functional association subject - gene, product or macromolecular complex that has the function associated with the GO term https://w3id.org/biolink/vocab/gene_as_a_model_of_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label gene as a model of disease association subject - A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease. https://w3id.org/biolink/vocab/gene_associated_with_condition http://www.w3.org/2000/01/rdf-schema#label gene associated with condition - holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with https://w3id.org/biolink/vocab/gene_expression_mixin_quantifier_qualifier http://www.w3.org/2000/01/rdf-schema#label gene expression mixin quantifier qualifier - Optional quantitative value indicating degree of expression. https://w3id.org/biolink/vocab/gene_fusion_with http://www.w3.org/2000/01/rdf-schema#label gene fusion with - holds between two independent genes that have fused through translocation, interstitial deletion, or chromosomal inversion to form a new, hybrid gene. Fusion genes are often implicated in various neoplasms and cancers. https://w3id.org/biolink/vocab/gene_has_variant_that_contributes_to_disease_association_object http://www.w3.org/2000/01/rdf-schema#label gene has variant that contributes to disease association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_has_variant_that_contributes_to_disease_association_predicate http://www.w3.org/2000/01/rdf-schema#label gene has variant that contributes to disease association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/gene_has_variant_that_contributes_to_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label gene has variant that contributes to disease association subject - A gene that has a role in modeling the disease. This may be a model organism ortholog of a known disease gene, or it may be a gene whose mutants recapitulate core features of the disease. https://w3id.org/biolink/vocab/gene_product_of http://www.w3.org/2000/01/rdf-schema#label gene product of - definition x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of thatf process is either y or something that is ribosomally translated from x https://w3id.org/biolink/vocab/gene_to_disease_association_object http://www.w3.org/2000/01/rdf-schema#label gene to disease association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to disease association subject - gene in which variation is correlated with the disease, may be protective or causative or associative, or as a model https://w3id.org/biolink/vocab/gene_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label gene to entity association mixin subject - gene that is the subject of the association https://w3id.org/biolink/vocab/gene_to_expression_site_association_object http://www.w3.org/2000/01/rdf-schema#label gene to expression site association object - location in which the gene is expressed https://w3id.org/biolink/vocab/gene_to_expression_site_association_predicate http://www.w3.org/2000/01/rdf-schema#label gene to expression site association predicate - expression relationship https://w3id.org/biolink/vocab/gene_to_expression_site_association_quantifier_qualifier http://www.w3.org/2000/01/rdf-schema#label gene to expression site association quantifier qualifier - can be used to indicate magnitude, or also ranking https://w3id.org/biolink/vocab/gene_to_expression_site_association_stage_qualifier http://www.w3.org/2000/01/rdf-schema#label gene to expression site association stage qualifier - stage at which the gene is expressed in the site https://w3id.org/biolink/vocab/gene_to_expression_site_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to expression site association subject - Gene or gene product positively within the specified anatomical entity (or subclass, i.e. cellular component) location. https://w3id.org/biolink/vocab/gene_to_gene_association_object http://www.w3.org/2000/01/rdf-schema#label gene to gene association object - the object gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa. https://w3id.org/biolink/vocab/gene_to_gene_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to gene association subject - the subject gene in the association. If the relation is symmetric, subject vs object is arbitrary. We allow a gene product to stand as a proxy for the gene or vice versa. https://w3id.org/biolink/vocab/gene_to_gene_coexpression_association_predicate http://www.w3.org/2000/01/rdf-schema#label gene to gene coexpression association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/gene_to_gene_family_association_object http://www.w3.org/2000/01/rdf-schema#label gene to gene family association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_gene_family_association_predicate http://www.w3.org/2000/01/rdf-schema#label gene to gene family association predicate - membership of the gene in the given gene family. https://w3id.org/biolink/vocab/gene_to_gene_family_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to gene family association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_gene_homology_association_object http://www.w3.org/2000/01/rdf-schema#label gene to gene homology association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_gene_homology_association_predicate http://www.w3.org/2000/01/rdf-schema#label gene to gene homology association predicate - homology relationship type https://w3id.org/biolink/vocab/gene_to_gene_homology_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to gene homology association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_gene_product_relationship_object http://www.w3.org/2000/01/rdf-schema#label gene to gene product relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_gene_product_relationship_predicate http://www.w3.org/2000/01/rdf-schema#label gene to gene product relationship predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/gene_to_gene_product_relationship_subject http://www.w3.org/2000/01/rdf-schema#label gene to gene product relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_go_term_association_object http://www.w3.org/2000/01/rdf-schema#label gene to go term association object - class describing the activity, process or localization of the gene product https://w3id.org/biolink/vocab/gene_to_go_term_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to go term association subject - gene, product or macromolecular complex that has the function associated with the GO term https://w3id.org/biolink/vocab/gene_to_pathway_association_object http://www.w3.org/2000/01/rdf-schema#label gene to pathway association object - the pathway that includes or is affected by the gene or gene product https://w3id.org/biolink/vocab/gene_to_pathway_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to pathway association subject - the gene or gene product entity that participates or influences the pathway https://w3id.org/biolink/vocab/gene_to_phenotypic_feature_association_object http://www.w3.org/2000/01/rdf-schema#label gene to phenotypic feature association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/gene_to_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label gene to phenotypic feature association subject - gene in which variation is correlated with the phenotypic feature https://w3id.org/biolink/vocab/genetic_association http://www.w3.org/2000/01/rdf-schema#label genetic association - Co-occurrence of a certain allele of a genetic marker and the phenotype of interest in the same individuals at above-chance level https://w3id.org/biolink/vocab/genetic_neighborhood_of http://www.w3.org/2000/01/rdf-schema#label genetic neighborhood of - holds between two genes located nearby one another on a chromosome. https://w3id.org/biolink/vocab/genetically_interacts_with http://www.w3.org/2000/01/rdf-schema#label genetically interacts with - holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality. https://w3id.org/biolink/vocab/genome_build http://www.w3.org/2000/01/rdf-schema#label genome build - The version of the genome on which a feature is located. For example, GRCh38 for Homo sapiens. https://w3id.org/biolink/vocab/genomic_sequence_localization_object http://www.w3.org/2000/01/rdf-schema#label genomic sequence localization object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/genomic_sequence_localization_predicate http://www.w3.org/2000/01/rdf-schema#label genomic sequence localization predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/genomic_sequence_localization_subject http://www.w3.org/2000/01/rdf-schema#label genomic sequence localization subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/genotype_as_a_model_of_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype as a model of disease association subject - A genotype that has a role in modeling the disease. https://w3id.org/biolink/vocab/genotype_to_disease_association_object http://www.w3.org/2000/01/rdf-schema#label genotype to disease association object - a disease that is associated with that genotype https://w3id.org/biolink/vocab/genotype_to_disease_association_predicate http://www.w3.org/2000/01/rdf-schema#label genotype to disease association predicate - E.g. is pathogenic for https://w3id.org/biolink/vocab/genotype_to_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype to disease association subject - a genotype that is associated in some way with a disease state https://w3id.org/biolink/vocab/genotype_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label genotype to entity association mixin subject - genotype that is the subject of the association https://w3id.org/biolink/vocab/genotype_to_gene_association_object http://www.w3.org/2000/01/rdf-schema#label genotype to gene association object - gene implicated in genotype https://w3id.org/biolink/vocab/genotype_to_gene_association_predicate http://www.w3.org/2000/01/rdf-schema#label genotype to gene association predicate - the relationship type used to connect genotype to gene https://w3id.org/biolink/vocab/genotype_to_gene_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype to gene association subject - parent genotype https://w3id.org/biolink/vocab/genotype_to_genotype_part_association_object http://www.w3.org/2000/01/rdf-schema#label genotype to genotype part association object - child genotype https://w3id.org/biolink/vocab/genotype_to_genotype_part_association_predicate http://www.w3.org/2000/01/rdf-schema#label genotype to genotype part association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/genotype_to_genotype_part_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype to genotype part association subject - parent genotype https://w3id.org/biolink/vocab/genotype_to_phenotypic_feature_association_predicate http://www.w3.org/2000/01/rdf-schema#label genotype to phenotypic feature association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/genotype_to_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype to phenotypic feature association subject - genotype that is associated with the phenotypic feature https://w3id.org/biolink/vocab/genotype_to_variant_association_object http://www.w3.org/2000/01/rdf-schema#label genotype to variant association object - gene implicated in genotype https://w3id.org/biolink/vocab/genotype_to_variant_association_predicate http://www.w3.org/2000/01/rdf-schema#label genotype to variant association predicate - the relationship type used to connect genotype to gene https://w3id.org/biolink/vocab/genotype_to_variant_association_subject http://www.w3.org/2000/01/rdf-schema#label genotype to variant association subject - parent genotype https://w3id.org/biolink/vocab/has_active_ingredient http://www.w3.org/2000/01/rdf-schema#label has active ingredient - holds between a drug and a molecular entity in which the latter is a part of the former, and is a biologically active component https://w3id.org/biolink/vocab/has_adverse_event http://www.w3.org/2000/01/rdf-schema#label has adverse event - An untoward medical occurrence in a patient or clinical investigation subject that happens during treatment with a therapeutic agent. Adverse events may be caused by something other than the drug or therapy being given and may include abnormal laboratory finding, symptoms, or diseases temporally associated with the treatment, whether or not considered related to the treatment. Adverse events are unintended effects that occur when a medication is administered correctly. https://w3id.org/biolink/vocab/has_attribute http://www.w3.org/2000/01/rdf-schema#label has attribute - connects any entity to an attribute https://w3id.org/biolink/vocab/has_attribute_type http://www.w3.org/2000/01/rdf-schema#label has attribute type - connects an attribute to a class that describes it https://w3id.org/biolink/vocab/has_biological_sequence http://www.w3.org/2000/01/rdf-schema#label has biological sequence - connects a genomic feature to its sequence https://w3id.org/biolink/vocab/has_biomarker http://www.w3.org/2000/01/rdf-schema#label has biomarker - holds between a disease or phenotypic feature and a measurable chemical entity that is used as an indicator of the presence or state of the disease or feature. # metabolite https://w3id.org/biolink/vocab/has_chemical_formula http://www.w3.org/2000/01/rdf-schema#label has chemical formula - description of chemical compound based on element symbols https://w3id.org/biolink/vocab/has_chemical_role http://www.w3.org/2000/01/rdf-schema#label has chemical role - A role is particular behaviour which a chemical entity may exhibit. https://w3id.org/biolink/vocab/has_completed http://www.w3.org/2000/01/rdf-schema#label has completed - holds between an entity and a process that the entity is capable of and has completed https://w3id.org/biolink/vocab/has_confidence_level http://www.w3.org/2000/01/rdf-schema#label has confidence level - connects an association to a qualitative term denoting the level of confidence https://w3id.org/biolink/vocab/has_constituent http://www.w3.org/2000/01/rdf-schema#label has constituent - one or more molecular entities within a chemical mixture https://w3id.org/biolink/vocab/has_count http://www.w3.org/2000/01/rdf-schema#label has count - number of things with a particular property https://w3id.org/biolink/vocab/has_device http://www.w3.org/2000/01/rdf-schema#label has device - connects an entity to one or more (medical) devices https://w3id.org/biolink/vocab/has_drug http://www.w3.org/2000/01/rdf-schema#label has drug - connects an entity to one or more drugs https://w3id.org/biolink/vocab/has_evidence http://www.w3.org/2000/01/rdf-schema#label has evidence - connects an association to an instance of supporting evidence https://w3id.org/biolink/vocab/has_excipient http://www.w3.org/2000/01/rdf-schema#label has excipient - holds between a drug and a molecular entities in which the latter is a part of the former, and is a biologically inactive component https://w3id.org/biolink/vocab/has_food_component http://www.w3.org/2000/01/rdf-schema#label has food component - holds between food and one or more chemical entities composing it, irrespective of nutritional value (i.e. could also be a contaminant or additive) https://w3id.org/biolink/vocab/has_gene http://www.w3.org/2000/01/rdf-schema#label has gene - connects an entity associated with one or more genes https://w3id.org/biolink/vocab/has_gene_or_gene_product http://www.w3.org/2000/01/rdf-schema#label has gene or gene product - connects an entity with one or more gene or gene products https://w3id.org/biolink/vocab/has_gene_product http://www.w3.org/2000/01/rdf-schema#label has gene product - holds between a gene and a transcribed and/or translated product generated from it https://w3id.org/biolink/vocab/has_input http://www.w3.org/2000/01/rdf-schema#label has input - holds between a process and a continuant, where the continuant is an input into the process https://w3id.org/biolink/vocab/has_member http://www.w3.org/2000/01/rdf-schema#label has member - Defines a mereological relation between a collection and an item. https://w3id.org/biolink/vocab/has_metabolite http://www.w3.org/2000/01/rdf-schema#label has metabolite - holds between two molecular entities in which the second one is derived from the first one as a product of metabolism https://w3id.org/biolink/vocab/has_mode_of_inheritance http://www.w3.org/2000/01/rdf-schema#label has mode of inheritance - Relates a disease or phenotypic feature to its observed genetic segregation and assumed associated underlying DNA manifestation (i.e. autosomal, sex or mitochondrial chromosome). https://w3id.org/biolink/vocab/has_molecular_consequence http://www.w3.org/2000/01/rdf-schema#label has molecular consequence - connects a sequence variant to a class describing the molecular consequence. E.g. SO:0001583 https://w3id.org/biolink/vocab/has_not_completed http://www.w3.org/2000/01/rdf-schema#label has not completed - holds between an entity and a process that the entity is capable of, but has not completed https://w3id.org/biolink/vocab/has_numeric_value http://www.w3.org/2000/01/rdf-schema#label has numeric value - connects a quantity value to a number https://w3id.org/biolink/vocab/has_nutrient http://www.w3.org/2000/01/rdf-schema#label has nutrient - one or more nutrients which are growth factors for a living organism https://w3id.org/biolink/vocab/has_output http://www.w3.org/2000/01/rdf-schema#label has output - holds between a process and a continuant, where the continuant is an output of the process https://w3id.org/biolink/vocab/has_part http://www.w3.org/2000/01/rdf-schema#label has part - holds between wholes and their parts (material entities or processes) https://w3id.org/biolink/vocab/has_participant http://www.w3.org/2000/01/rdf-schema#label has participant - holds between a process and a continuant, where the continuant is somehow involved in the process https://w3id.org/biolink/vocab/has_percentage http://www.w3.org/2000/01/rdf-schema#label has percentage - equivalent to has quotient multiplied by 100 https://w3id.org/biolink/vocab/has_phenotype http://www.w3.org/2000/01/rdf-schema#label has phenotype - holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). In SNOMEDCT, disorders with keyword 'characterized by' should translate into this predicate. https://w3id.org/biolink/vocab/has_plasma_membrane_part http://www.w3.org/2000/01/rdf-schema#label has plasma membrane part - Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. https://w3id.org/biolink/vocab/has_procedure http://www.w3.org/2000/01/rdf-schema#label has procedure - connects an entity to one or more (medical) procedures https://w3id.org/biolink/vocab/has_qualitative_value http://www.w3.org/2000/01/rdf-schema#label has qualitative value - connects an attribute to a value https://w3id.org/biolink/vocab/has_quantitative_value http://www.w3.org/2000/01/rdf-schema#label has quantitative value - connects an attribute to a value https://w3id.org/biolink/vocab/has_receptor http://www.w3.org/2000/01/rdf-schema#label has receptor - the organism or organism part being exposed https://w3id.org/biolink/vocab/has_route http://www.w3.org/2000/01/rdf-schema#label has route - the process that results in the stressor coming into direct contact with the receptor https://w3id.org/biolink/vocab/has_sequence_location http://www.w3.org/2000/01/rdf-schema#label has sequence location - holds between two nucleic acid entities when the subject can be localized in sequence coordinates on the object. For example, between an exon and a chromosome/contig. https://w3id.org/biolink/vocab/has_side_effect http://www.w3.org/2000/01/rdf-schema#label has side effect - An unintended, but predictable, secondary effect shown to be correlated with a therapeutic agent, drug or treatment. Side effects happen at normal, recommended doses or treatments, and are unrelated to the intended purpose of the medication. https://w3id.org/biolink/vocab/has_stressor http://www.w3.org/2000/01/rdf-schema#label has stressor - the process or entity that the receptor is being exposed to https://w3id.org/biolink/vocab/has_supporting_study_result http://www.w3.org/2000/01/rdf-schema#label has supporting study result - connects an association to an instance of supporting study result https://w3id.org/biolink/vocab/has_topic http://www.w3.org/2000/01/rdf-schema#label has topic - Connects a node to a vocabulary term or ontology class that describes some aspect of the entity. In general specific characterization is preferred. See https://github.com/biolink/biolink-model/issues/238 https://w3id.org/biolink/vocab/has_total http://www.w3.org/2000/01/rdf-schema#label has total - total number of things in a particular reference set https://w3id.org/biolink/vocab/has_unit http://www.w3.org/2000/01/rdf-schema#label has unit - connects a quantity value to a unit https://w3id.org/biolink/vocab/has_variant_part http://www.w3.org/2000/01/rdf-schema#label has variant part - holds between a nucleic acid entity and a nucleic acid entity that is a sub-component of it https://w3id.org/biolink/vocab/highest_FDA_approval_status http://www.w3.org/2000/01/rdf-schema#label highest FDA approval status - Should be the highest level of FDA approval this chemical entity or device has, regardless of which disease, condition or phenotype it is currently being reviewed to treat. For specific levels of FDA approval for a specific condition, disease, phenotype, etc., see the association slot, 'FDA approval status.' https://w3id.org/biolink/vocab/homologous_to http://www.w3.org/2000/01/rdf-schema#label homologous to - holds between two biological entities that have common evolutionary origin https://w3id.org/biolink/vocab/id http://www.w3.org/2000/01/rdf-schema#label id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI https://w3id.org/biolink/vocab/in_cell_population_with http://www.w3.org/2000/01/rdf-schema#label in cell population with - holds between two genes or gene products that are expressed in the same cell type or population https://w3id.org/biolink/vocab/in_complex_with http://www.w3.org/2000/01/rdf-schema#label in complex with - holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex https://w3id.org/biolink/vocab/in_linkage_disequilibrium_with http://www.w3.org/2000/01/rdf-schema#label in linkage disequilibrium with - holds between two sequence variants, the presence of which are correlated in a population https://w3id.org/biolink/vocab/in_pathway_with http://www.w3.org/2000/01/rdf-schema#label in pathway with - holds between two genes or gene products that are part of in the same biological pathway https://w3id.org/biolink/vocab/in_taxon http://www.w3.org/2000/01/rdf-schema#label in taxon - connects an entity to its taxonomic classification. Only certain kinds of entities can be taxonomically classified; see 'thing with taxon' https://w3id.org/biolink/vocab/increased_likelihood_associated_with http://www.w3.org/2000/01/rdf-schema#label increased likelihood associated with - https://w3id.org/biolink/vocab/increases_amount_or_activity_of http://www.w3.org/2000/01/rdf-schema#label increases amount or activity of - A grouping mixin to help with searching for all the predicates that increase the amount or activity of the object. https://w3id.org/biolink/vocab/increases_response_to http://www.w3.org/2000/01/rdf-schema#label increases response to - holds between two chemical entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other https://w3id.org/biolink/vocab/information_content_entity_to_named_thing_association_object http://www.w3.org/2000/01/rdf-schema#label information content entity to named thing association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/information_content_entity_to_named_thing_association_predicate http://www.w3.org/2000/01/rdf-schema#label information content entity to named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/information_content_entity_to_named_thing_association_subject http://www.w3.org/2000/01/rdf-schema#label information content entity to named thing association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/interacts_with http://www.w3.org/2000/01/rdf-schema#label interacts with - holds between any two entities that directly or indirectly interact with each other https://w3id.org/biolink/vocab/interbase_coordinate http://www.w3.org/2000/01/rdf-schema#label interbase coordinate - A position in interbase coordinates. Interbase coordinates start at position 0 instead of position 1. This is applied to a sequence localization edge. https://w3id.org/biolink/vocab/iri http://www.w3.org/2000/01/rdf-schema#label iri - An IRI for an entity. This is determined by the id using expansion rules. https://w3id.org/biolink/vocab/is_active_ingredient_of http://www.w3.org/2000/01/rdf-schema#label is active ingredient of - holds between a molecular entity and a drug, in which the former is a part of the latter, and is a biologically active component https://w3id.org/biolink/vocab/is_excipient_of http://www.w3.org/2000/01/rdf-schema#label is excipient of - holds between a molecular entity and a drug in which the former is a part of the latter, and is a biologically inactive component https://w3id.org/biolink/vocab/is_frameshift_variant_of http://www.w3.org/2000/01/rdf-schema#label is frameshift variant of - holds between a sequence variant and a gene, such the sequence variant causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three. https://w3id.org/biolink/vocab/is_metabolite http://www.w3.org/2000/01/rdf-schema#label is metabolite - indicates whether a molecular entity is a metabolite https://w3id.org/biolink/vocab/is_metabolite_of http://www.w3.org/2000/01/rdf-schema#label is metabolite of - holds between two molecular entities in which the first one is derived from the second one as a product of metabolism https://w3id.org/biolink/vocab/is_missense_variant_of http://www.w3.org/2000/01/rdf-schema#label is missense variant of - holds between a gene and a sequence variant, such the sequence variant results in a different amino acid sequence but where the length is preserved. https://w3id.org/biolink/vocab/is_nearby_variant_of http://www.w3.org/2000/01/rdf-schema#label is nearby variant of - holds between a sequence variant and a gene sequence that the variant is genomically close to. https://w3id.org/biolink/vocab/is_non_coding_variant_of http://www.w3.org/2000/01/rdf-schema#label is non coding variant of - holds between a sequence variant and a gene, where the variant does not affect the coding sequence https://w3id.org/biolink/vocab/is_nonsense_variant_of http://www.w3.org/2000/01/rdf-schema#label is nonsense variant of - holds between a sequence variant and a gene, such the sequence variant results in a premature stop codon https://w3id.org/biolink/vocab/is_sequence_variant_of http://www.w3.org/2000/01/rdf-schema#label is sequence variant of - holds between a sequence variant and a nucleic acid entity https://w3id.org/biolink/vocab/is_splice_site_variant_of http://www.w3.org/2000/01/rdf-schema#label is splice site variant of - holds between a sequence variant and a gene, such the sequence variant is in the canonical splice site of one of the gene's exons. https://w3id.org/biolink/vocab/is_supplement http://www.w3.org/2000/01/rdf-schema#label is supplement - https://w3id.org/biolink/vocab/is_synonymous_variant_of http://www.w3.org/2000/01/rdf-schema#label is synonymous variant of - holds between a sequence variant and a gene, such the sequence variant is in the coding sequence of the gene, but results in the same amino acid sequence https://w3id.org/biolink/vocab/is_toxic http://www.w3.org/2000/01/rdf-schema#label is toxic - https://w3id.org/biolink/vocab/iso_abbreviation http://www.w3.org/2000/01/rdf-schema#label iso abbreviation - Standard abbreviation for periodicals in the International Organization for Standardization (ISO) 4 system See https://www.issn.org/services/online-services/access-to-the-ltwa/. If the 'published in' property is set, then the iso abbreviation pertains to the broader publication context (the journal) within which the given publication node is embedded, not the publication itself. https://w3id.org/biolink/vocab/issue http://www.w3.org/2000/01/rdf-schema#label issue - issue of a newspaper, a scientific journal or magazine for reference purpose https://w3id.org/biolink/vocab/keywords http://www.w3.org/2000/01/rdf-schema#label keywords - keywords tagging a publication https://w3id.org/biolink/vocab/knowledge_source http://www.w3.org/2000/01/rdf-schema#label knowledge source - An Information Resource from which the knowledge expressed in an Association was retrieved, directly or indirectly. This can be any resource through which the knowledge passed on its way to its currently serialized form. In practice, implementers should use one of the more specific subtypes of this generic property. https://w3id.org/biolink/vocab/latitude http://www.w3.org/2000/01/rdf-schema#label latitude - latitude https://w3id.org/biolink/vocab/likelihood_associated_with http://www.w3.org/2000/01/rdf-schema#label likelihood associated with - https://w3id.org/biolink/vocab/ln_ratio http://www.w3.org/2000/01/rdf-schema#label ln ratio - the natural log of the ratio of co-occurrence to expected https://w3id.org/biolink/vocab/ln_ratio_confidence_interval http://www.w3.org/2000/01/rdf-schema#label ln ratio confidence interval - The 99% confidence interval for the ln_ratio calculation (i.e. the range of values within which the true value has a 99% chance of falling) https://w3id.org/biolink/vocab/located_in http://www.w3.org/2000/01/rdf-schema#label located in - holds between a material entity and a material entity or site within which it is located (but of which it is not considered a part) https://w3id.org/biolink/vocab/location_of http://www.w3.org/2000/01/rdf-schema#label location of - holds between material entity or site and a material entity that is located within it (but not considered a part of it) https://w3id.org/biolink/vocab/longitude http://www.w3.org/2000/01/rdf-schema#label longitude - longitude https://w3id.org/biolink/vocab/macromolecular_machine_mixin_name http://www.w3.org/2000/01/rdf-schema#label macromolecular machine mixin name - genes are typically designated by a short symbol and a full name. We map the symbol to the default display name and use an additional slot for full name https://w3id.org/biolink/vocab/macromolecular_machine_to_biological_process_association_object http://www.w3.org/2000/01/rdf-schema#label macromolecular machine to biological process association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/macromolecular_machine_to_cellular_component_association_object http://www.w3.org/2000/01/rdf-schema#label macromolecular machine to cellular component association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/macromolecular_machine_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label macromolecular machine to entity association mixin subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/macromolecular_machine_to_molecular_activity_association_object http://www.w3.org/2000/01/rdf-schema#label macromolecular machine to molecular activity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/manifestation_of http://www.w3.org/2000/01/rdf-schema#label manifestation of - that part of a phenomenon which is directly observable or visibly expressed, or which gives evidence to the underlying process; used in SemMedDB for linking things like dysfunctions and processes to some disease or syndrome https://w3id.org/biolink/vocab/mapped_predicate http://www.w3.org/2000/01/rdf-schema#label mapped predicate - The predicate that is being replaced by the fully qualified representation of predicate + subject and object qualifiers. Only to be used in test data and mapping data to help with the transition to the fully qualified predicate model. Not to be used in knowledge graphs. https://w3id.org/biolink/vocab/material_sample_derivation_association_object http://www.w3.org/2000/01/rdf-schema#label material sample derivation association object - the material entity the sample was derived from. This may be another material sample, or any other material entity, including for example an organism, a geographic feature, or some environmental material. https://w3id.org/biolink/vocab/material_sample_derivation_association_predicate http://www.w3.org/2000/01/rdf-schema#label material sample derivation association predicate - derivation relationship https://w3id.org/biolink/vocab/material_sample_derivation_association_subject http://www.w3.org/2000/01/rdf-schema#label material sample derivation association subject - the material sample being described https://w3id.org/biolink/vocab/material_sample_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label material sample to entity association mixin subject - the material sample being described https://w3id.org/biolink/vocab/max_tolerated_dose http://www.w3.org/2000/01/rdf-schema#label max tolerated dose - The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD. https://w3id.org/biolink/vocab/mechanism_of_action http://www.w3.org/2000/01/rdf-schema#label mechanism of action - a boolean flag to indicate if the edge is part of a path or subgraph of a knowledge graph that constitutes the mechanism of action for a result. https://w3id.org/biolink/vocab/member_of http://www.w3.org/2000/01/rdf-schema#label member of - Defines a mereological relation between a item and a collection. https://w3id.org/biolink/vocab/mentioned_by http://www.w3.org/2000/01/rdf-schema#label mentioned by - refers to is a relation between one named thing and the information content entity that it makes reference to. https://w3id.org/biolink/vocab/mentions http://www.w3.org/2000/01/rdf-schema#label mentions - refers to is a relation between one information content entity and the named thing that it makes reference to. https://w3id.org/biolink/vocab/mesh_terms http://www.w3.org/2000/01/rdf-schema#label mesh terms - mesh terms tagging a publication https://w3id.org/biolink/vocab/model_of http://www.w3.org/2000/01/rdf-schema#label model of - holds between a thing and some other thing it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity. https://w3id.org/biolink/vocab/model_to_disease_association_mixin_predicate http://www.w3.org/2000/01/rdf-schema#label model to disease association mixin predicate - The relationship to the disease https://w3id.org/biolink/vocab/model_to_disease_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label model to disease association mixin subject - The entity that serves as the model of the disease. This may be an organism, a strain of organism, a genotype or variant that exhibits similar features, or a gene that when mutated exhibits features of the disease https://w3id.org/biolink/vocab/molecular_activity_enabled_by http://www.w3.org/2000/01/rdf-schema#label molecular activity enabled by - The gene product, gene, or complex that catalyzes the reaction https://w3id.org/biolink/vocab/molecular_activity_has_input http://www.w3.org/2000/01/rdf-schema#label molecular activity has input - A chemical entity that is the input for the reaction https://w3id.org/biolink/vocab/molecular_activity_has_output http://www.w3.org/2000/01/rdf-schema#label molecular activity has output - A chemical entity that is the output for the reaction https://w3id.org/biolink/vocab/molecular_activity_to_chemical_entity_association_object http://www.w3.org/2000/01/rdf-schema#label molecular activity to chemical entity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/molecular_activity_to_chemical_entity_association_subject http://www.w3.org/2000/01/rdf-schema#label molecular activity to chemical entity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/molecular_activity_to_molecular_activity_association_object http://www.w3.org/2000/01/rdf-schema#label molecular activity to molecular activity association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/molecular_activity_to_molecular_activity_association_subject http://www.w3.org/2000/01/rdf-schema#label molecular activity to molecular activity association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/molecular_activity_to_pathway_association_object http://www.w3.org/2000/01/rdf-schema#label molecular activity to pathway association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/molecular_activity_to_pathway_association_predicate http://www.w3.org/2000/01/rdf-schema#label molecular activity to pathway association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/molecular_activity_to_pathway_association_subject http://www.w3.org/2000/01/rdf-schema#label molecular activity to pathway association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/name http://www.w3.org/2000/01/rdf-schema#label name - A human-readable name for an attribute or entity. https://w3id.org/biolink/vocab/named_thing_associated_with_likelihood_of_named_thing_association_predicate http://www.w3.org/2000/01/rdf-schema#label named thing associated with likelihood of named thing association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/named_thing_category http://www.w3.org/2000/01/rdf-schema#label named thing category - Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. * In a neo4j database this MAY correspond to the neo4j label tag. * In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values `biolink:Protein`, `biolink:GeneProduct`, `biolink:MolecularEntity`, ... In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature `f` may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing} https://w3id.org/biolink/vocab/narrow_match http://www.w3.org/2000/01/rdf-schema#label narrow match - a list of terms from different schemas or terminology systems that have a narrower, more specific meaning. Narrower terms are typically shown as children in a hierarchy or tree. https://w3id.org/biolink/vocab/narrow_matches http://www.w3.org/2000/01/rdf-schema#label narrow matches - A list of terms from different schemas or terminology systems that have a narrower meaning. Such terms often describe a more specific concept from different ontological perspectives. https://w3id.org/biolink/vocab/negated http://www.w3.org/2000/01/rdf-schema#label negated - if set to true, then the association is negated i.e. is not true https://w3id.org/biolink/vocab/negatively_correlated_with http://www.w3.org/2000/01/rdf-schema#label negatively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move in opposite directions (i.e. increased in one or presence of one correlates with a decrease or absence of the other). https://w3id.org/biolink/vocab/node_property http://www.w3.org/2000/01/rdf-schema#label node property - A grouping for any property that holds between a node and a value https://w3id.org/biolink/vocab/nutrient_of http://www.w3.org/2000/01/rdf-schema#label nutrient of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive) https://w3id.org/biolink/vocab/object http://www.w3.org/2000/01/rdf-schema#label object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/object_location_in_text http://www.w3.org/2000/01/rdf-schema#label object location in text - Character offsets for the text span(s) in the supporting text corresponding to the object concept of the extracted assertion https://w3id.org/biolink/vocab/occurs_in http://www.w3.org/2000/01/rdf-schema#label occurs in - holds between a process and a material entity or site within which the process occurs https://w3id.org/biolink/vocab/occurs_together_in_literature_with http://www.w3.org/2000/01/rdf-schema#label occurs together in literature with - holds between two entities where their co-occurrence is correlated by counts of publications in which both occur, using some threshold of occurrence as defined by the edge provider. https://w3id.org/biolink/vocab/onset_qualifier http://www.w3.org/2000/01/rdf-schema#label onset qualifier - a qualifier used in a phenotypic association to state when the phenotype appears is in the subject https://w3id.org/biolink/vocab/opposite_of http://www.w3.org/2000/01/rdf-schema#label opposite of - x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). (This description is from RO. Needs to be rephrased). https://w3id.org/biolink/vocab/organism_taxon_to_entity_association_subject http://www.w3.org/2000/01/rdf-schema#label organism taxon to entity association subject - organism taxon that is the subject of the association https://w3id.org/biolink/vocab/organism_taxon_to_environment_association_object http://www.w3.org/2000/01/rdf-schema#label organism taxon to environment association object - the environment in which the organism occurs https://w3id.org/biolink/vocab/organism_taxon_to_environment_association_predicate http://www.w3.org/2000/01/rdf-schema#label organism taxon to environment association predicate - predicate describing the relationship between the taxon and the environment https://w3id.org/biolink/vocab/organism_taxon_to_environment_association_subject http://www.w3.org/2000/01/rdf-schema#label organism taxon to environment association subject - the taxon that is the subject of the association https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_association_object http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_association_subject http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_interaction_associated_environmental_context http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon interaction associated environmental context - the environment in which the two taxa interact https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_interaction_object http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon interaction object - the taxon that is the subject of the association https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_interaction_predicate http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon interaction predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_interaction_subject http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon interaction subject - the taxon that is the subject of the association https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_specialization_object http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon specialization object - the more general taxon https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_specialization_predicate http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon specialization predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/organism_taxon_to_organism_taxon_specialization_subject http://www.w3.org/2000/01/rdf-schema#label organism taxon to organism taxon specialization subject - the more specific taxon https://w3id.org/biolink/vocab/organism_to_organism_association_object http://www.w3.org/2000/01/rdf-schema#label organism to organism association object - An association between two individual organisms. https://w3id.org/biolink/vocab/organism_to_organism_association_subject http://www.w3.org/2000/01/rdf-schema#label organism to organism association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/organismal_entity_as_a_model_of_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label organismal entity as a model of disease association subject - A organismal entity (strain, breed) with a predisposition to a disease, or bred/created specifically to model a disease. https://w3id.org/biolink/vocab/organismal_entity_has_attribute http://www.w3.org/2000/01/rdf-schema#label organismal entity has attribute - may often be an organism attribute https://w3id.org/biolink/vocab/original_object http://www.w3.org/2000/01/rdf-schema#label original object - used to hold the original object of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. https://w3id.org/biolink/vocab/original_predicate http://www.w3.org/2000/01/rdf-schema#label original predicate - used to hold the original relation/predicate that an external knowledge source uses before transformation to match the biolink-model specification. https://w3id.org/biolink/vocab/original_subject http://www.w3.org/2000/01/rdf-schema#label original subject - used to hold the original subject of a relation (or predicate) that an external knowledge source uses before transformation to match the biolink-model specification. https://w3id.org/biolink/vocab/orthologous_to http://www.w3.org/2000/01/rdf-schema#label orthologous to - a homology relationship between entities (typically genes) that diverged after a speciation event. https://w3id.org/biolink/vocab/overlaps http://www.w3.org/2000/01/rdf-schema#label overlaps - holds between entities that overlap in their extents (materials or processes) https://w3id.org/biolink/vocab/p_value http://www.w3.org/2000/01/rdf-schema#label p value - A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. https://w3id.org/biolink/vocab/pages http://www.w3.org/2000/01/rdf-schema#label pages - page number of source referenced for statement or publication https://w3id.org/biolink/vocab/pairwise_gene_to_gene_interaction_predicate http://www.w3.org/2000/01/rdf-schema#label pairwise gene to gene interaction predicate - interaction relationship type https://w3id.org/biolink/vocab/pairwise_molecular_interaction_id http://www.w3.org/2000/01/rdf-schema#label pairwise molecular interaction id - identifier for the interaction. This may come from an interaction database such as IMEX. https://w3id.org/biolink/vocab/pairwise_molecular_interaction_object http://www.w3.org/2000/01/rdf-schema#label pairwise molecular interaction object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/pairwise_molecular_interaction_predicate http://www.w3.org/2000/01/rdf-schema#label pairwise molecular interaction predicate - interaction relationship type https://w3id.org/biolink/vocab/pairwise_molecular_interaction_subject http://www.w3.org/2000/01/rdf-schema#label pairwise molecular interaction subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/paralogous_to http://www.w3.org/2000/01/rdf-schema#label paralogous to - a homology relationship that holds between entities (typically genes) that diverged after a duplication event. https://w3id.org/biolink/vocab/part_of http://www.w3.org/2000/01/rdf-schema#label part of - holds between parts and wholes (material entities or processes) https://w3id.org/biolink/vocab/part_qualifier http://www.w3.org/2000/01/rdf-schema#label part qualifier - defines a specific part/component of the core concept (used in cases there this specific part has no IRI we can use to directly represent it, e.g. 'ESR1 transcript' q: polyA tail). https://w3id.org/biolink/vocab/participates_in http://www.w3.org/2000/01/rdf-schema#label participates in - holds between a continuant and a process, where the continuant is somehow involved in the process https://w3id.org/biolink/vocab/phase http://www.w3.org/2000/01/rdf-schema#label phase - The phase for a coding sequence entity. For example, phase of a CDS as represented in a GFF3 with a value of 0, 1 or 2. https://w3id.org/biolink/vocab/phenotypic_state http://www.w3.org/2000/01/rdf-schema#label phenotypic state - in experiments (e.g. gene expression) assaying diseased or unhealthy tissue, the phenotypic state can be put here, e.g. MONDO ID. For healthy tissues, use XXX. https://w3id.org/biolink/vocab/physically_interacts_with http://www.w3.org/2000/01/rdf-schema#label physically interacts with - holds between two entities that make physical contact as part of some interaction. does not imply a causal relationship. https://w3id.org/biolink/vocab/population_context_qualifier http://www.w3.org/2000/01/rdf-schema#label population context qualifier - a biological population (general, study, cohort, etc.) with a specific set of characteristics to constrain an association. https://w3id.org/biolink/vocab/population_to_population_association_object http://www.w3.org/2000/01/rdf-schema#label population to population association object - the population that form the object of the association https://w3id.org/biolink/vocab/population_to_population_association_predicate http://www.w3.org/2000/01/rdf-schema#label population to population association predicate - A relationship type that holds between the subject and object populations. Standard mereological relations can be used. E.g. subject part-of object, subject overlaps object. Derivation relationships can also be used https://w3id.org/biolink/vocab/population_to_population_association_subject http://www.w3.org/2000/01/rdf-schema#label population to population association subject - the population that form the subject of the association https://w3id.org/biolink/vocab/positively_correlated_with http://www.w3.org/2000/01/rdf-schema#label positively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move together in the same direction (i.e. increased in one or presence of one correlates with an increase or presence of the other). https://w3id.org/biolink/vocab/preceded_by http://www.w3.org/2000/01/rdf-schema#label preceded by - holds between two processes, where the other is completed before the one begins https://w3id.org/biolink/vocab/precedes http://www.w3.org/2000/01/rdf-schema#label precedes - holds between two processes, where one completes before the other begins https://w3id.org/biolink/vocab/predicate http://www.w3.org/2000/01/rdf-schema#label predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/predicate_mappings http://www.w3.org/2000/01/rdf-schema#label predicate mappings - A collection of relationships that are not used in biolink, but have biolink patterns that can be used to replace them. This is a temporary slot to help with the transition to the fully qualified predicate model in Biolink3. https://w3id.org/biolink/vocab/predisposes http://www.w3.org/2000/01/rdf-schema#label predisposes - holds between two entities where exposure to one entity increases the chance of developing the other https://w3id.org/biolink/vocab/prevented_by http://www.w3.org/2000/01/rdf-schema#label prevented by - holds between a potential outcome of which the likelihood was reduced by the application or use of an entity. https://w3id.org/biolink/vocab/prevents http://www.w3.org/2000/01/rdf-schema#label prevents - holds between an entity whose application or use reduces the likelihood of a potential outcome. Typically used to associate a chemical entity, exposure, activity, or medical intervention that can prevent the onset a disease or phenotypic feature. https://w3id.org/biolink/vocab/primary_knowledge_source http://www.w3.org/2000/01/rdf-schema#label primary knowledge source - The most upstream source of the knowledge expressed in an Association that an implementer can identify. Performing a rigorous analysis of upstream data providers is expected; every effort is made to catalog the most upstream source of data in this property. Only one data source should be declared primary in any association. "aggregator knowledge source" can be used to caputre non-primary sources. https://w3id.org/biolink/vocab/produces http://www.w3.org/2000/01/rdf-schema#label produces - holds between a material entity and a product that is generated through the intentional actions or functioning of the material entity https://w3id.org/biolink/vocab/provided_by http://www.w3.org/2000/01/rdf-schema#label provided by - The value in this node property represents the knowledge provider that created or assembled the node and all of its attributes. Used internally to represent how a particular node made its way into a knowledge provider or graph. https://w3id.org/biolink/vocab/provider http://www.w3.org/2000/01/rdf-schema#label provider - person, group, organization or project that provides a piece of information (e.g. a knowledge association). https://w3id.org/biolink/vocab/publication_id http://www.w3.org/2000/01/rdf-schema#label publication id - Different kinds of publication subtypes will have different preferred identifiers (curies when feasible). Precedence of identifiers for scientific articles is as follows: PMID if available; DOI if not; actual alternate CURIE otherwise. Enclosing publications (i.e. referenced by 'published in' node property) such as books and journals, should have industry-standard identifier such as from ISBN and ISSN. https://w3id.org/biolink/vocab/publication_name http://www.w3.org/2000/01/rdf-schema#label publication name - the 'title' of the publication is generally recorded in the 'name' property (inherited from NamedThing). The field name 'title' is now also tagged as an acceptable alias for the node property 'name' (just in case). https://w3id.org/biolink/vocab/publication_pages http://www.w3.org/2000/01/rdf-schema#label publication pages - When a 2-tuple of page numbers are provided, they represent the start and end page of the publication within its parent publication context. For books, this may be set to the total number of pages of the book. https://w3id.org/biolink/vocab/publication_publication_type http://www.w3.org/2000/01/rdf-schema#label publication publication type - Ontology term for publication type may be drawn from Dublin Core types (https://www.dublincore.org/specifications/dublin-core/dcmi-type-vocabulary/), FRBR-aligned Bibliographic Ontology (https://sparontologies.github.io/fabio/current/fabio.html), the MESH publication types (https://www.nlm.nih.gov/mesh/pubtypes.html), the Confederation of Open Access Repositories (COAR) Controlled Vocabulary for Resource Type Genres (http://vocabularies.coar-repositories.org/documentation/resource_types/), Wikidata (https://www.wikidata.org/wiki/Wikidata:Publication_types), or equivalent publication type ontology. When a given publication type ontology term is used within a given knowledge graph, then the CURIE identified term must be documented in the graph as a concept node of biolink:category biolink:OntologyClass. https://w3id.org/biolink/vocab/publication_type http://www.w3.org/2000/01/rdf-schema#label publication type - Ontology term for publication type may be drawn from Dublin Core types (https://www.dublincore.org/specifications/dublin-core/dcmi-type-vocabulary/), FRBR-aligned Bibliographic Ontology (https://sparontologies.github.io/fabio/current/fabio.html), the MESH publication types (https://www.nlm.nih.gov/mesh/pubtypes.html), the Confederation of Open Access Repositories (COAR) Controlled Vocabulary for Resource Type Genres (http://vocabularies.coar-repositories.org/documentation/resource_types/), Wikidata (https://www.wikidata.org/wiki/Wikidata:Publication_types), or equivalent publication type ontology. When a given publication type ontology term is used within a given knowledge graph, then the CURIE identified term must be documented in the graph as a concept node of biolink:category biolink:OntologyClass. https://w3id.org/biolink/vocab/publications http://www.w3.org/2000/01/rdf-schema#label publications - One or more publications that report the statement expressed in an Association, or provide information used as evidence supporting this statement. https://w3id.org/biolink/vocab/published_in http://www.w3.org/2000/01/rdf-schema#label published in - CURIE identifier of a broader publication context within which the publication may be placed, e.g. a specified book or journal. https://w3id.org/biolink/vocab/publisher http://www.w3.org/2000/01/rdf-schema#label publisher - organization or person responsible for publishing books, periodicals, podcasts, games or software. Note that in the case of publications which have a containing "published in" node property, the publisher association may not be attached directly to the embedded child publication, but only made in between the parent's publication node and the publisher agent of the encompassing publication (e.g. only from the Journal referenced by the 'published_in' property of an journal article Publication node). https://w3id.org/biolink/vocab/qualified_predicate http://www.w3.org/2000/01/rdf-schema#label qualified predicate - Predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading. This qualifier holds a relationship to be used instead of that expressed by the primary predicate, in a ‘full statement’ reading of the association, where qualifier-based semantics are included. This is necessary only in cases where the primary predicate does not work in a full statement reading. https://w3id.org/biolink/vocab/qualifier http://www.w3.org/2000/01/rdf-schema#label qualifier - grouping slot for all qualifiers on an edge. useful for testing compliance with association classes https://w3id.org/biolink/vocab/qualifiers http://www.w3.org/2000/01/rdf-schema#label qualifiers - connects an association to qualifiers that modify or qualify the meaning of that association https://w3id.org/biolink/vocab/quantifier_qualifier http://www.w3.org/2000/01/rdf-schema#label quantifier qualifier - A measurable quantity for the object of the association https://w3id.org/biolink/vocab/reaction_direction http://www.w3.org/2000/01/rdf-schema#label reaction direction - the direction of a reaction as constrained by the direction enum (ie: left_to_right, neutral, etc.) https://w3id.org/biolink/vocab/reaction_side http://www.w3.org/2000/01/rdf-schema#label reaction side - the side of a reaction being modeled (ie: left or right) https://w3id.org/biolink/vocab/reaction_to_catalyst_association_object http://www.w3.org/2000/01/rdf-schema#label reaction to catalyst association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/reaction_to_participant_association_subject http://www.w3.org/2000/01/rdf-schema#label reaction to participant association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/regulates http://www.w3.org/2000/01/rdf-schema#label regulates - A more specific form of affects, that implies the effect results from a biologically evolved control mechanism. Gene-affects-gene relationships will (almost) always involve regulation. Exogenous/environmental chemical-affects-gene relationships are not cases of regulation in this definition. Instead these would be captured using the 'affects' predicate, or possibly one of the 'interacts with' predicates depending on the nature of the interaction. https://w3id.org/biolink/vocab/related_to http://www.w3.org/2000/01/rdf-schema#label related to - A relationship that is asserted between two named things https://w3id.org/biolink/vocab/related_to_at_concept_level http://www.w3.org/2000/01/rdf-schema#label related to at concept level - Represents a relationship held between terminology components that describe the conceptual model of a domain. https://w3id.org/biolink/vocab/related_to_at_instance_level http://www.w3.org/2000/01/rdf-schema#label related to at instance level - Represents a relationship held between two instances of a data classes. Much like an assertion component, in an ABox, these represent facts associated with the conceptual model. https://w3id.org/biolink/vocab/relative_frequency_object http://www.w3.org/2000/01/rdf-schema#label relative frequency object - The frequency at which subject and object concepts co-occur in records within a dataset/cohort, relative to the frequency at which the object concept appears in these same records. https://w3id.org/biolink/vocab/relative_frequency_object_confidence_interval http://www.w3.org/2000/01/rdf-schema#label relative frequency object confidence interval - The 99% confidence interval for the relative_frequency_object calculation (i.e. the range of values within which the true value has a 99% chance of falling) https://w3id.org/biolink/vocab/relative_frequency_subject http://www.w3.org/2000/01/rdf-schema#label relative frequency subject - The frequency at which subject and object concepts co-occur in records within a dataset/cohort, relative to the frequency at which the subject concept appears in these same records. https://w3id.org/biolink/vocab/relative_frequency_subject_confidence_interval http://www.w3.org/2000/01/rdf-schema#label relative frequency subject confidence interval - The 99% confidence interval for the relative_frequency_subject calculation (i.e. the range of values within which the true value has a 99% chance of falling) https://w3id.org/biolink/vocab/resource http://www.w3.org/2000/01/rdf-schema#label resource - The CURIE for an Information Resource that served as a source of knowledge expressed in an Edge, or a source of data used to generate this knowledge. https://w3id.org/biolink/vocab/resource_role http://www.w3.org/2000/01/rdf-schema#label resource role - The role played by the InformationResource in serving as a source for an Edge. Note that a given Edge should have one and only one 'primary' source, and may have any number of 'aggregator' or 'supporting data' sources. https://w3id.org/biolink/vocab/response_affected_by http://www.w3.org/2000/01/rdf-schema#label response affected by - holds between two chemical entities where the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) of one is affected by the action of the other. https://w3id.org/biolink/vocab/retrieval_source_resource http://www.w3.org/2000/01/rdf-schema#label retrieval source resource - The InformationResource that served as a source for the knowledge expressed in an Edge, or data used to generate this knowledge. https://w3id.org/biolink/vocab/retrieval_source_resource_role http://www.w3.org/2000/01/rdf-schema#label retrieval source resource role - The role of the InformationResource in the retrieval of the knowledge expressed in an Edge, or data used to generate this knowledge. https://w3id.org/biolink/vocab/retrieval_source_upstream_resources http://www.w3.org/2000/01/rdf-schema#label retrieval source upstream resources - The InformationResources that served as a source for the InformationResource that served as a source for the knowledge expressed in an Edge, or data used to generate this knowledge. https://w3id.org/biolink/vocab/routes_of_delivery http://www.w3.org/2000/01/rdf-schema#label routes of delivery - the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. https://w3id.org/biolink/vocab/same_as http://www.w3.org/2000/01/rdf-schema#label same as - holds between two entities that are considered equivalent to each other https://w3id.org/biolink/vocab/sequence_feature_relationship_object http://www.w3.org/2000/01/rdf-schema#label sequence feature relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/sequence_feature_relationship_subject http://www.w3.org/2000/01/rdf-schema#label sequence feature relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/sequence_localization_attribute http://www.w3.org/2000/01/rdf-schema#label sequence localization attribute - An attribute that can be applied to a genome sequence localization edge. These edges connect a nucleic acid entity such as an exon to an entity such as a chromosome. Edge properties are used to ascribe specific positional information and other metadata to the localization. In pragmatic terms this can be thought of as columns in a GFF3 line. https://w3id.org/biolink/vocab/sequence_variant_has_biological_sequence http://www.w3.org/2000/01/rdf-schema#label sequence variant has biological sequence - The state of the sequence w.r.t a reference sequence https://w3id.org/biolink/vocab/sequence_variant_has_gene http://www.w3.org/2000/01/rdf-schema#label sequence variant has gene - Each allele can be associated with any number of genes https://w3id.org/biolink/vocab/sequence_variant_id http://www.w3.org/2000/01/rdf-schema#label sequence variant id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI https://w3id.org/biolink/vocab/sequence_variant_modulates_treatment_association_object http://www.w3.org/2000/01/rdf-schema#label sequence variant modulates treatment association object - treatment whose efficacy is modulated by the subject variant https://w3id.org/biolink/vocab/sequence_variant_modulates_treatment_association_subject http://www.w3.org/2000/01/rdf-schema#label sequence variant modulates treatment association subject - variant that modulates the treatment of some disease https://w3id.org/biolink/vocab/sequence_variant_qualifier http://www.w3.org/2000/01/rdf-schema#label sequence variant qualifier - a qualifier used in an association with the variant https://w3id.org/biolink/vocab/serial_id http://www.w3.org/2000/01/rdf-schema#label serial id - Serials (journals) should have industry-standard identifier such as from ISSN. https://w3id.org/biolink/vocab/serial_type http://www.w3.org/2000/01/rdf-schema#label serial type - Should generally be set to an ontology class defined term for 'serial' or 'journal'. https://w3id.org/biolink/vocab/severity_qualifier http://www.w3.org/2000/01/rdf-schema#label severity qualifier - a qualifier used in a phenotypic association to state how severe the phenotype is in the subject https://w3id.org/biolink/vocab/sex_qualifier http://www.w3.org/2000/01/rdf-schema#label sex qualifier - a qualifier used in a phenotypic association to state whether the association is specific to a particular sex. https://w3id.org/biolink/vocab/similar_to http://www.w3.org/2000/01/rdf-schema#label similar to - holds between an entity and some other entity with similar features. https://w3id.org/biolink/vocab/small_molecule_id http://www.w3.org/2000/01/rdf-schema#label small molecule id - A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI https://w3id.org/biolink/vocab/socioeconomic_exposure_has_attribute http://www.w3.org/2000/01/rdf-schema#label socioeconomic exposure has attribute - connects any entity to an attribute https://w3id.org/biolink/vocab/species_context_qualifier http://www.w3.org/2000/01/rdf-schema#label species context qualifier - A statement qualifier representing a taxonomic category of species in which a relationship expressed in an association took place. https://w3id.org/biolink/vocab/stage_qualifier http://www.w3.org/2000/01/rdf-schema#label stage qualifier - stage during which gene or protein expression of takes place. https://w3id.org/biolink/vocab/start_coordinate http://www.w3.org/2000/01/rdf-schema#label start coordinate - The position at which the subject genomic entity starts on the chromosome or other entity to which it is located on. (ie: the start of the sequence being referenced is 1). https://w3id.org/biolink/vocab/start_interbase_coordinate http://www.w3.org/2000/01/rdf-schema#label start interbase coordinate - The position at which the subject nucleic acid entity starts on the chromosome or other entity to which it is located on. (ie: the start of the sequence being referenced is 0). https://w3id.org/biolink/vocab/statement_qualifier http://www.w3.org/2000/01/rdf-schema#label statement qualifier - https://w3id.org/biolink/vocab/stoichiometry http://www.w3.org/2000/01/rdf-schema#label stoichiometry - the relationship between the relative quantities of substances taking part in a reaction or forming a compound, typically a ratio of whole integers. https://w3id.org/biolink/vocab/strand http://www.w3.org/2000/01/rdf-schema#label strand - The strand on which a feature is located. Has a value of '+' (sense strand or forward strand) or '-' (anti-sense strand or reverse strand). https://w3id.org/biolink/vocab/subclass_of http://www.w3.org/2000/01/rdf-schema#label subclass of - holds between two classes where the domain class is a specialization of the range class https://w3id.org/biolink/vocab/subject http://www.w3.org/2000/01/rdf-schema#label subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/subject_location_in_text http://www.w3.org/2000/01/rdf-schema#label subject location in text - Character offsets for the text span(s) in the supporting text corresponding to the subject concept of the extracted assertion. https://w3id.org/biolink/vocab/summary http://www.w3.org/2000/01/rdf-schema#label summary - executive summary of a publication https://w3id.org/biolink/vocab/superclass_of http://www.w3.org/2000/01/rdf-schema#label superclass of - holds between two classes where the domain class is a super class of the range class https://w3id.org/biolink/vocab/support_graphs http://www.w3.org/2000/01/rdf-schema#label support graphs - A list of knowledge graphs that support the existence of this node. https://w3id.org/biolink/vocab/supporting_data_set http://www.w3.org/2000/01/rdf-schema#label supporting data set - A set of data used as evidence to generate the knowledge expressed in an Association (e.g. through computation on, reasoning or inference over the retrieved data). https://w3id.org/biolink/vocab/supporting_data_source http://www.w3.org/2000/01/rdf-schema#label supporting data source - An Information Resource from which data was retrieved and subsequently used as evidence to generate the knowledge expressed in an Association (e.g. through computation on, reasoning or inference over the retrieved data). https://w3id.org/biolink/vocab/supporting_document_type http://www.w3.org/2000/01/rdf-schema#label supporting document type - The document type (e.g., Journal Article, Case Study, Preprint) for the supporting document used in a Text Mining Result. https://w3id.org/biolink/vocab/supporting_document_year http://www.w3.org/2000/01/rdf-schema#label supporting document year - The document year (typically the publication year) for the supporting document used in a Text Mining Result. https://w3id.org/biolink/vocab/supporting_documents http://www.w3.org/2000/01/rdf-schema#label supporting documents - One or more referencable documents that report the statement expressed in an Association, or provide information used as evidence supporting this statement. https://w3id.org/biolink/vocab/supporting_study_cohort http://www.w3.org/2000/01/rdf-schema#label supporting study cohort - A description of a study population/cohort that was interrogated to provide evidence for the association (e.g. the inclusion and exclusion criteria). https://w3id.org/biolink/vocab/supporting_study_context http://www.w3.org/2000/01/rdf-schema#label supporting study context - A term or terms describing the experimental setting/context in which evidence supporting the Association was generated ('context' may be defined by many factors, including taxon, model system (e.g. cell line type), tissue type, disease, etc.). https://w3id.org/biolink/vocab/supporting_study_date_range http://www.w3.org/2000/01/rdf-schema#label supporting study date range - The date range over which data was collected in a study that provided evidence for an Association. https://w3id.org/biolink/vocab/supporting_study_metadata http://www.w3.org/2000/01/rdf-schema#label supporting study metadata - Information about a study used to generate information used as evidence to support the knowledge expressed in an Association. In practice, data creators should use one of the more specific subtypes of this property. https://w3id.org/biolink/vocab/supporting_study_method_description http://www.w3.org/2000/01/rdf-schema#label supporting study method description - A uri or curie pointing to information about the methodology used to generate data supporting an Association. https://w3id.org/biolink/vocab/supporting_study_method_type http://www.w3.org/2000/01/rdf-schema#label supporting study method type - A type of method that was applied in a study used to generate the information used as evidence (e.g. a type of experimental assay, or statistical calculation, or computational analysis). https://w3id.org/biolink/vocab/supporting_study_size http://www.w3.org/2000/01/rdf-schema#label supporting study size - The sample size used in a study that provided evidence for the association (e.g. 'n' of a cohort for a clinical study). https://w3id.org/biolink/vocab/supporting_text http://www.w3.org/2000/01/rdf-schema#label supporting text - The segment of text from a document that supports the mined assertion. https://w3id.org/biolink/vocab/supporting_text_section_type http://www.w3.org/2000/01/rdf-schema#label supporting text section type - The section of the supporting text of a Text Mining Result within the supporting document. This is in the form of the name of the document section (e.g., Abstract, Introduction) that contains the supporting text. https://w3id.org/biolink/vocab/symbol http://www.w3.org/2000/01/rdf-schema#label symbol - Symbol for a particular thing https://w3id.org/biolink/vocab/synonym http://www.w3.org/2000/01/rdf-schema#label synonym - Alternate human-readable names for a thing https://w3id.org/biolink/vocab/systematic_synonym http://www.w3.org/2000/01/rdf-schema#label systematic synonym - more commonly used for gene symbols in yeast https://w3id.org/biolink/vocab/target_for http://www.w3.org/2000/01/rdf-schema#label target for - A gene is a target of a disease when its products are druggable and when a drug interaction with the gene product could have a therapeutic effect https://w3id.org/biolink/vocab/taxon_to_taxon_association_object http://www.w3.org/2000/01/rdf-schema#label taxon to taxon association object - An association between individuals of different taxa. https://w3id.org/biolink/vocab/taxon_to_taxon_association_subject http://www.w3.org/2000/01/rdf-schema#label taxon to taxon association subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/temporal_context_qualifier http://www.w3.org/2000/01/rdf-schema#label temporal context qualifier - a constraint of time placed upon the truth value of an association. for time intervales, use temporal interval qualifier. https://w3id.org/biolink/vocab/temporal_interval_qualifier http://www.w3.org/2000/01/rdf-schema#label temporal interval qualifier - a constraint of a time interval placed upon the truth value of an association. https://w3id.org/biolink/vocab/temporally_related_to http://www.w3.org/2000/01/rdf-schema#label temporally related to - holds between two entities with a temporal relationship https://w3id.org/biolink/vocab/timepoint http://www.w3.org/2000/01/rdf-schema#label timepoint - a point in time https://w3id.org/biolink/vocab/trade_name http://www.w3.org/2000/01/rdf-schema#label trade name - https://w3id.org/biolink/vocab/transcribed_from http://www.w3.org/2000/01/rdf-schema#label transcribed from - x is transcribed from y if and only if x is synthesized from template y https://w3id.org/biolink/vocab/transcribed_to http://www.w3.org/2000/01/rdf-schema#label transcribed to - inverse of transcribed from https://w3id.org/biolink/vocab/transcript_to_gene_relationship_object http://www.w3.org/2000/01/rdf-schema#label transcript to gene relationship object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/transcript_to_gene_relationship_subject http://www.w3.org/2000/01/rdf-schema#label transcript to gene relationship subject - connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/translates_to http://www.w3.org/2000/01/rdf-schema#label translates to - x (amino acid chain/polypeptide) is the ribosomal translation of y (transcript) if and only if a ribosome reads y (transcript) through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces x (amino acid chain/polypeptide) https://w3id.org/biolink/vocab/translation_of http://www.w3.org/2000/01/rdf-schema#label translation of - inverse of translates to https://w3id.org/biolink/vocab/treated_by http://www.w3.org/2000/01/rdf-schema#label treated by - holds between a disease or phenotypic feature and a therapeutic process or chemical entity that is used to treat the condition https://w3id.org/biolink/vocab/treats http://www.w3.org/2000/01/rdf-schema#label treats - holds between a therapeutic procedure or chemical entity and a disease or phenotypic feature that it is used to treat https://w3id.org/biolink/vocab/update_date http://www.w3.org/2000/01/rdf-schema#label update date - date on which an entity was updated. This can be applied to nodes or edges https://w3id.org/biolink/vocab/upstream_resources http://www.w3.org/2000/01/rdf-schema#label upstream resources - An upstream InformationResource from which the resource being described directly retrieved a record of the knowledge expressed in the Edge, or data used to generate this knowledge. This is an array because there are cases where a merged Edge holds knowledge that was retrieved from multiple sources. e.g. an Edge provided by the ARAGORN ARA can expressing knowledge it retrieved from both the automat-mychem-info and molepro KPs, which both provided it with records of this single fact. https://w3id.org/biolink/vocab/variant_as_a_model_of_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label variant as a model of disease association subject - A variant that has a role in modeling the disease. https://w3id.org/biolink/vocab/variant_to_disease_association_object http://www.w3.org/2000/01/rdf-schema#label variant to disease association object - a disease that is associated with that variant https://w3id.org/biolink/vocab/variant_to_disease_association_predicate http://www.w3.org/2000/01/rdf-schema#label variant to disease association predicate - E.g. is pathogenic for https://w3id.org/biolink/vocab/variant_to_disease_association_subject http://www.w3.org/2000/01/rdf-schema#label variant to disease association subject - a sequence variant in which the allele state is associated in some way with the disease state https://w3id.org/biolink/vocab/variant_to_entity_association_mixin_subject http://www.w3.org/2000/01/rdf-schema#label variant to entity association mixin subject - a sequence variant in which the allele state is associated with some other entity https://w3id.org/biolink/vocab/variant_to_gene_association_object http://www.w3.org/2000/01/rdf-schema#label variant to gene association object - connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object. https://w3id.org/biolink/vocab/variant_to_gene_association_predicate http://www.w3.org/2000/01/rdf-schema#label variant to gene association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/variant_to_gene_expression_association_predicate http://www.w3.org/2000/01/rdf-schema#label variant to gene expression association predicate - A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes. https://w3id.org/biolink/vocab/variant_to_phenotypic_feature_association_subject http://www.w3.org/2000/01/rdf-schema#label variant to phenotypic feature association subject - a sequence variant in which the allele state is associated in some way with the phenotype state https://w3id.org/biolink/vocab/variant_to_population_association_has_count http://www.w3.org/2000/01/rdf-schema#label variant to population association has count - number in object population that carry a particular allele, aka allele count https://w3id.org/biolink/vocab/variant_to_population_association_has_quotient http://www.w3.org/2000/01/rdf-schema#label variant to population association has quotient - frequency of allele in population, expressed as a number with allele divided by number in reference population, aka allele frequency https://w3id.org/biolink/vocab/variant_to_population_association_has_total http://www.w3.org/2000/01/rdf-schema#label variant to population association has total - number all populations that carry a particular allele, aka allele number https://w3id.org/biolink/vocab/variant_to_population_association_object http://www.w3.org/2000/01/rdf-schema#label variant to population association object - the population that is observed to have the frequency https://w3id.org/biolink/vocab/variant_to_population_association_subject http://www.w3.org/2000/01/rdf-schema#label variant to population association subject - an allele that has a certain frequency in a given population https://w3id.org/biolink/vocab/volume http://www.w3.org/2000/01/rdf-schema#label volume - volume of a book or music release in a collection/series or a published collection of journal issues in a serial publication https://w3id.org/biolink/vocab/xenologous_to http://www.w3.org/2000/01/rdf-schema#label xenologous to - a homology relationship characterized by an interspecies (horizontal) transfer since the common ancestor. https://w3id.org/biolink/vocab/xref http://www.w3.org/2000/01/rdf-schema#label xref - Alternate CURIEs for a thing http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#provenance http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#assertion http://www.w3.org/ns/prov#wasDerivedFrom https://raw.githubusercontent.com/biolink/biolink-model/master/biolink-model.ttl http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#pubinfo http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#sig http://purl.org/nanopub/x/hasAlgorithm RSA http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#sig http://purl.org/nanopub/x/hasPublicKey MIGfMA0GCSqGSIb3DQEBAQUAA4GNADCBiQKBgQCwUtewGCpT5vIfXYE1bmf/Uqu1ojqnWdYxv+ySO80ul8Gu7m8KoyPAwuvaPj0lvPtHrg000qMmkxzKhYknEjq8v7EerxZNYp5B3/3+5ZpuWOYAs78UnQVjbHSmDdmryr4D4VvvNIiUmd0yxci47dTFUj4DvfHnGd6hVe5+goqdcwIDAQAB http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#sig http://purl.org/nanopub/x/hasSignature ZyeFvXIpYeGgQkl3kNfsrbfCW9BKWlY/3UbXaQec60RafxgQxyH86aSt8WfrW6G35aZxEVsASrDKb4E7c8a2NMRJkVafnkZ77puckYo7zmDgyNrw3Ggv+8YI0WfA4x1zU5+YL1oOZnCPAbEkCuBqIoNN15tnYUizrea7667ShAY= http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M#sig http://purl.org/nanopub/x/hasSignatureTarget http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://purl.org/dc/terms/created 2023-03-31T14:24:26.976+02:00 http://purl.org/np/RArAFrdM4rux7Cwl-lT_a4JzGk9tcGItbpd7ykkbD3S2M http://purl.org/dc/terms/creator https://orcid.org/0000-0002-1267-0234