. . . . . . . . . . . . . . . "kin(p(PFH:\"AKT Family\")) -> bp(GO:\"cell proliferation\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Serine 167 in AF1 is also phosphorylated, this time by the 90-kDa ribosomal S6 kinase RSK 89, which is itself activated by ERK1 and ERK2. Another signalling pathway that might have an important role in ER activity is the phosphatidylinositol- 3-OH kinase (PI3K) signalling pathway. The serine/threonine protein kinase AKT (or PKB) is one of the downstream targets of PI3K97. Its activation promotes cellular proliferation and anti-apoptotic responses. ER phosphorylation by AKT occurs at serine 167 and results in ligand-independent activation of ER98,99." . . "Selventa" . . . . "2014-07-03T14:30:11.000+02:00"^^ . . .