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[In this editorial review, we present data supporting the hypothesis that impaired apoE4 function modulates A?-induced effects on inflammatory receptor signaling, including amplification of detrimental (TLR4-p38?) and suppression of beneficial (IL-4R-nuclear receptor) pathways, resulting in an adverse NIP that causes neuronal dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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Gene-disease associations inferred from text-mining the literature.
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