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kin(p(HGNC:EGFR)) -> gtp(p(HGNC:NRAS))
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Approximately 61,000 statements.
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1.4
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After activating Ras using EGF, the GTP-bound form of Ras was precipitated with GST-RBD (GST-Raf containing Ras binding domain). Precipitated Ras was detected using the HA-antibody. As shown in Fig. 5D, in the presence of EGF, the amount of GTP-bound Ras increased over that of the control. Levels of the GTP-bound Ras significantly decreased in cells expressing DIP1/2; however, DIP1/2m failed to stimulate Ras GTPase in cells treated with EGF.
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Selventa
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2014-07-03T14:30:00.713+02:00
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