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r(HGNC:LEP) -| p(HGNC:RETN)
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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1.4
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Resistin appears to be an important regulator of glucose homeostasis, adipogenesis, and, potentially, inflammation [65, 66]. Obesity induced by a high fat diet, mutation of the leptin gene (ob-/ob- mice), or the leptin receptor gene (db-/db- mice) is associated with increased circulating resistin concentrations [50]. Resistin induces insulin resistance in mice and regulates the deposition of adipose tissue through a negative feedback mechanism.
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Selventa
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2014-07-03T14:30:35.646+02:00
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