http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#Head http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#provenance http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#pubinfo http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_1 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=5464 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_2 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_3 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0016301 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_3 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=6877 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_4 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_2 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_1 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.w3.org/2000/01/rdf-schema#label p(HGNC:IGF1) -> kin(p(HGNC:MAPK3)) http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#provenance http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_6 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_5 http://www.w3.org/ns/prov#value LDL, in pathophysiological concentrations, affect the IGF-I signaling pathway at multiple levels: 1) they induce phosphorylation of IGF-I receptor beta and IRS-1 in a time- and dose-dependent manner; 2) they up-regulate IRS-1-associated PI3 kinase/Akt activation in response to IGF-I at early times; and 3) they show additive effects with IGF-I on extracellular signal-regulated MAPK 1/2 phosphorylation. http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11606453 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11606453 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#_5 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA#pubinfo http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://purl.org/dc/terms/created 2014-07-03T14:29:58.658+02:00 http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAtXegB29C9W6cuaQOptoDtbbTBeQAsY7YTww2SwR_xXA http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234