sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_5 prov:value " Here, as a first step toward pinpointing this role, we have employed two-dimensional tryptic mapping to directly identify the major sites of Src-induced p120 phosphorylation. Eight sites were identified by direct mutation of candidate tyrosines to phenylalanine and elimination of the accompanying spots on the two-dimensional maps. Identical sites were observed in vitro and in vivo, strongly suggesting that the physiologically important sites have been correctly identified. (Next section taken from Results - Fig 4) Mutation of tyrosines 112, 228, and 280 to phenylalanine resulted in elimination of phosphopeptide spots 6, 7, and 8, respectively. Mutation of tyrosine 96 eliminated spots 9 and 10, whereas mutation of tyrosine 257 eliminated spots 4 and 5...These results suggest that peptides 1, 2, and 3 represent singly, doubly, and triply phosphorylated variants, respectively, of the same peptide, containing Tyr291, Tyr296, and Tyr302. " ;
prov:wasQuotedFrom pubmed:11382764 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:11382764 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}