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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#_3 http://www.w3.org/ns/prov#value we demonstrate that SR-BI prevents NO-induced cytotoxicity and that a highly conserved CXXS redox motif is required for the anti-NO cytotoxicity activity of SR-BI. Using genetically manipulated mice, we demonstrate that SR-BI-null mice have a 3- to 4-fold increase in tyrosine nitrated proteins in aorta and liver compared with wild-type littermates, indicating that expression of SR-BI prevents peroxynitrite formation in vivo. http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/16574909 http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/16574909 http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#_3 http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0#pubinfo http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0 http://purl.org/dc/terms/created 2014-07-03T14:30:42.507+02:00 http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0 http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAuZXbrpI8AtXkwGVYqRotsmCBuUgz3Eaa0J3mVy89VP0 http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234