sub:provenance {
beldoc: dce:description "Approximately 61,000 statements." ;
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title "BEL Framework Large Corpus Document" ;
pav:authoredBy sub:_6 ;
pav:version "1.4" .
sub:_5 prov:value "Activation of mTOR by insulin results in phosphorylation of downstream targets, e.g. 4E-BP1, S6K1 and ribosomal protein S6, resulting in activation of the mRNA-binding steps in translation initiation. Activation of the phosphatidylinositol 3-kinase-mammalian target of rapamycin signalling pathway by amino acids Although it is clear that amino acids, and in particular leucine, enhance phosphorylation of proteins downstream of mTOR, e.g. 4E-BP1 and S6K1, and indeed require mTOR to be active in order to be effective, whether or not they directly regulate mTOR activity is undecided." ;
prov:wasQuotedFrom pubmed:15294054 .
sub:_6 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:15294054 ;
prov:wasDerivedFrom beldoc: ,
sub:_5 .
}