. . . . . . . "[Presenilin-1 (PS1) and presenilin-2 (PS2) are transmembrane proteins widely expressed in the central nervous system, which function as the catalytic subunits of ?-secretase, the enzyme that releases amyloid-? protein (A?) from ectodomain cleaved amyloid precursor protein (APP) by intramembrane proteolysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:10:37+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .