. . . . . . . . . . . . . . . "p(HGNC:RNF14) => tscript(p(HGNC:AR))" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "1.4" . "Kang et al. (1999) demonstrated that the ARA54 gene (RNF14; 605675) can function as a coactivator for androgen-dependent transcription on both wildtype and mutant androgen receptor. They found that in the presence of a certain amount of 17-beta-estradiol or hydroxyflutamide, the transcriptional activity of a specific AR mutant was significantly enhanced, whereas that of wildtype and another AR mutant was not. They therefore suggested that both ARA54 and the positions of the AR mutation might contribute to the specificity of AR-mediated transactivation. Coexpression of ARA54 with other AR coactivators, such as ARA70 (601984) and SRC1 (602691), showed additive stimulation of AR-mediated transactivation, indicating that these cofactors may function individually as AR coactivators to induce AR target gene expression." . . "Selventa" . . . . "2014-07-03T14:29:46.285+02:00"^^ . . .